SCHEMBL2936934

SCHEMBL2936934

Oc1c(Br)cccc1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.62
MAPK1 P28482 2/20 0.62
HDAC4 P56524 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HNF4A P41235 1/20 0.53
HSD17B10 Q99714 2/20 0.50
HPGD P15428 1/20 0.50
BCL2L1 Q07817 1/20 0.50
CRHBP P24387 1/20 0.50
CRHR2 Q13324 1/20 0.50
BACE1 P56817 3/20 0.46
AKR1C3 P42330 2/20 0.43
AKR1C2 P52895 2/20 0.43
AKR1C1 Q04828 2/20 0.43
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL27768973 0.92 ALDH1A1 (0.54) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL11323890 0.83 CA1 (0.45) ALDH1A1MAPK1HSD17B10HPGDCRHBP
SCHEMBL60283 0.83 HDAC4 (0.65) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL30605196 0.83 HDAC4 (0.65) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL27784006 0.82 ALDH1A1 (0.50) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL3805586 0.80 HDAC4 (0.62) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL9487300 0.80 HDAC4 (0.62) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL30834671 0.80 HDAC4 (0.62) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL8559182 0.80 HDAC4 (0.62) ALDH1A1MAPK1HDAC4HDAC2HDAC8
SCHEMBL30688232 0.80 HDAC4 (0.62) ALDH1A1MAPK1HDAC4HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106147314-A A kind of aluminum alloy doors and windows coating material 余志娟 2016-11-23 CN claimed
EP-1494995-B1 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS PROCTER & GAMBLE (US) 2010-09-22 EP claimed
US-20250179059-A1 ANTICANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
US-12162870-B2 Anticancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-12-10 US disclosed
CN-111699177-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2024-08-20 CN disclosed
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2024-06-25 US disclosed
CN-113549010-B Preparation and application of compound with AMPK (AMPK) agonistic activity and prodrug thereof 中国科学院上海药物研究所 2023-10-20 CN disclosed
US-20230025178-A1 ANTICANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-01-26 US disclosed
US-20220384729-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2022-12-01 US disclosed
US-7241715-B2 Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom SYMYX TECHNOLOGIES, INC. (US) 2007-07-10 US disclosed
EP-1498178-A2 Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex and process for producing olefin polymers Sumitomo Chemical Company, Limited (JP) 2005-01-19 EP disclosed
CN-1185236-C Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2005-01-19 CN disclosed
EP-0842939-B1 OLEFIN POLYMERIZATION CATALYST CONTAINING A TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6329478-B1 SOLUBILITY IN SATURATED HYDROCARBON SOLVENTS SUMITMO CHEMICAL COMPANY, LIMITED 2001-12-11 US disclosed
CN-1310183-A Transition metal compound, its producing process olefine polymerization catalyst containing the same transition metal compound and process for producing olefine polymer SUMITOMO CHEMICAL CO (JP) 2001-08-29 CN disclosed
CN-1068884-C Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 2001-07-25 CN disclosed
CN-1193323-A Transition metal complex, process for producing the same, olefin polymerization catalyst containing the transition metal complex, and process for producing olefin polymer SUMITOMO CHEM IND (JP) 1998-09-16 CN disclosed
EP-0842939-A1 TRANSITION METAL COMPLEX, PROCESS FOR THE PREPARATION THEREOF, POLYMERIZATION CATALYST FOR OLEFINS CONTAINING THE COMPLEX, AND PROCESS FOR PRODUCING OLEFIN POLYMERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-05-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179059-A1 ANTICANCER COMPOUNDS BET1, BRD4, BICRA ALDH1A1 3346/4885MAPK1 2457/4885HDAC4 456/4885
US-20230025178-A1 ANTICANCER COMPOUNDS BET1, BRD4, BICRA ALDH1A1 3346/4885MAPK1 2457/4885HDAC4 456/4885
US-12022729-B2 Compound for organic electric element, organic electric element comprising the same, and electronic device thereof PIEZO1, VDAC2, ORAI2 ALDH1A1 1855/4885MAPK1 2173/4885HDAC4 1375/4885
US-12162870-B2 Anticancer compounds BET1, BRD4, BICRA ALDH1A1 3346/4885MAPK1 2457/4885HDAC4 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.