Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763308 | 0.88 | ESR1 (0.34) | — | |
| SCHEMBL29704594 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL8764224 | 0.78 | TRPA1 (0.39) | TRPA1TSHRKMT2AMIFTAAR1 | |
| SCHEMBL8053155 | 0.78 | LMNA (0.38) | ALDH1A1LMNAHPGD | |
| SCHEMBL5229583 | 0.77 | HDAC4 (0.38) | ALDH1A1 | |
| SCHEMBL22811521 | 0.77 | CYP19A1 (0.47) | TSHRKDM4ELMNA | |
| SCHEMBL21424550 | 0.77 | CYP19A1 (0.47) | TSHRKDM4ELMNA | |
| SCHEMBL31261419 | 0.75 | KDM4E (0.48) | TSHRKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL19646056 | 0.73 | TSHR (0.52) | TRPA1TSHRL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL880926 | 0.72 | LMNA (0.42) | TRPA1TSHRKMT2AMIFTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103444759-B | Isorhodanate and matrine mixture and its application | WUHAN LELIJI BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-02-25 | — | — | CN | disclosed |
| CN-103444759-A | Isorhodanate and matrine mixture and its application | WUHAN LELIJI BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |