Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 3/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | POLG | P54098 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912858 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Lb80380 SCHEMBL29355183 | 0.84 | FAP (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Lb80380 SCHEMBL4270816 | 0.84 | FAP (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2912291 | 0.84 | ABCB11 (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2907772 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL5942177 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| Maleic Acid SCHEMBL4395451 | 0.81 | FAP (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4415990 | 0.81 | ABCB11 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL4419762 | 0.81 | ABCB11 (0.40) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2906952 | 0.80 | ABCB11 (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | disclosed |