Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 3/20 | 0.58 |
| ▸ | NPY2R | P49146 | 8/20 | 0.57 |
| ▸ | NPY4R | P50391 | 8/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.57 |
| ▸ | NPY1R | P25929 | 6/20 | 0.57 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.55 |
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | TFPI | P10646 | 3/20 | 0.54 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29352548 | 0.92 | KEAP1 (0.62) | KEAP1 | |
| SCHEMBL31182846 | 0.89 | NPY2R (0.62) | MAPK8MAPK9MAPK10KDM1ANPY2R | |
| SCHEMBL29549424 | 0.89 | KDM1A (0.61) | KDM1ANPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30576992 | 0.89 | KDM1A (0.64) | KDM1ANPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30310002 | 0.88 | NPY2R (0.66) | MAPK8MAPK9MAPK10KDM1ANPY2R | |
| SCHEMBL30495741 | 0.88 | KDM1A (0.70) | KDM1ANPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL31182777 | 0.88 | MAPK8 (0.64) | MAPK8MAPK9MAPK10KDM1ANPY2R | |
| SCHEMBL30536329 | 0.87 | KDM1A (0.57) | KDM1ANPY2RNPY4RNPY5RNPY1R | |
| SCHEMBL30262082 | 0.87 | RAMP3 (0.65) | MAPK8MAPK9MAPK10NPY2RNPY4R | |
| SCHEMBL30423109 | 0.87 | APLNR (0.60) | MAPK8MAPK9MAPK10NPY2RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127851-A1 | CYTOKINE MODULATION | INFLAMMX THERAPEUTICS, INC. | 2025-04-24 | — | — | US | disclosed |
| US-20220288163-A1 | CYTOKINE MODULATION | INFLAMMX THERAPEUTICS, INC. | 2022-09-15 | — | — | US | disclosed |
| US-11344603-B2 | Cytokine modulation | AUCKLAND UNISERVICES LIMITED (NZ) | 2022-05-31 | — | — | US | disclosed |
| CN-114025786-A | Compositions and methods for protecting epithelial and barrier integrity | 欧耐柯萨斯医疗有限公司 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250127851-A1 | CYTOKINE MODULATION | TNF, IL2, IL1B | MAPK8 1908/4885MAPK9 2266/4885MAPK10 1277/4885 |
| US-20220288163-A1 | CYTOKINE MODULATION | TNF, IL2, IL1B | MAPK8 1908/4885MAPK9 2266/4885MAPK10 1277/4885 |
| US-11344603-B2 | Cytokine modulation | TNF, IL2, IL1B | MAPK8 1908/4885MAPK9 2266/4885MAPK10 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.