Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | GOT1 | P17174 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | MPO | P05164 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | THPO | P40225 | 1/20 | 0.57 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.57 |
| ▸ | ACOX1 | Q15067 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3918436 | 0.89 | POLB (0.58) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL3758755 | 0.85 | APP (0.57) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL29372940 | 0.85 | APP (0.57) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL3753974 | 0.79 | APP (0.60) | TP53SMN1; SMN2NPC1MPORAB9A | |
| SCHEMBL4987535 | 0.79 | CSNK2A1 (0.57) | ALDH1A1TP53KMT2AMEN1EGFR | |
| SCHEMBL5067187 | 0.77 | EGFR (0.52) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL12199237 | 0.77 | MPO (0.57) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL28900093 | 0.76 | NPC1 (0.71) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL13286756 | 0.76 | NPC1 (0.71) | KDM4EALDH1A1TP53CYP3A4GOT1 | |
| SCHEMBL2492808 | 0.76 | PDE5A (0.58) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014814-B | N-benzyl-4-phenylphthalazin-1-amine derivative, preparation method thereof and medicament for treating RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2023-07-25 | — | — | CN | disclosed |
| CN-114014814-A | N-benzyl-4-phenylphthalazin-1-amine derivative, preparation method thereof and medicine for treating RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2022-02-08 | — | — | CN | disclosed |