SCHEMBL29372126

SCHEMBL29372126

CC[C@H](C)[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 2/20 0.61
▸ CDK2 P24941 2/20 0.61
▸ CCNA1 P78396 2/20 0.61
▸ GRIN2D O15399 1/20 0.56
▸ GRIN3B O60391 1/20 0.56
▸ GRIN1 Q05586 1/20 0.56
▸ GRIN2A Q12879 1/20 0.56
▸ GRIN2B Q13224 1/20 0.56
▸ GRIN2C Q14957 1/20 0.56
▸ GRIN3A Q8TCU5 1/20 0.56
▸ ESR1 P03372 3/20 0.56
▸ ESR2 Q92731 2/20 0.56
▸ VIPR1 P32241 4/20 0.54
▸ VIPR2 P41587 6/20 0.53
▸ PTH1R Q03431 3/20 0.51
▸ AGTR1 P30556 1/20 0.50
▸ AGTR2 P50052 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30343041 0.86 CCNA2 (0.57) CCNA2CDK2CCNA1ESR1VIPR1
SCHEMBL29933691 0.85 VIPR2 (0.61) CCNA2CDK2CCNA1ESR1ESR2
SCHEMBL29736049 0.85 CCNA2 (0.65) CCNA2CDK2CCNA1VIPR1VIPR2
SCHEMBL29574453 0.83 PTH1R (0.63) VIPR1VIPR2PTH1R
SCHEMBL30623152 0.83 VIPR1 (0.68) VIPR1VIPR2
SCHEMBL29702256 0.82 CCNA2 (0.69) CCNA2CDK2CCNA1AGTR1AGTR2
SCHEMBL23083920 0.81 CCNA2 (0.58) CCNA2CDK2CCNA1GRIN2DGRIN3B
SCHEMBL29988328 0.81 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29375791 0.81 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL29986050 0.81 GRIN2D (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 393 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724572-A1 ENGINEERED CELLS WITH ENHANCED TEAD PROTEIN TRANSCRIPTIONAL ACTIVITIES AND METHODS OF USE THEREOF Legend Biotech Ireland Limited (IE) 2026-04-15 — — EP claimed
US-12577609-B2 Methods for cell-type specific profiling to identify drug targets THE ROCKEFELLER UNIVERSITY (US) 2026-03-17 — — US claimed
EP-4689188-A2 ACTIVE SURVEILLANCE AND RISK STRATIFICATION FOR PROSTATE CANCER Immunis.AI, Inc. (US) 2026-02-11 — — EP claimed
US-12411144-B2 Compositions and methods for treatment of lung function CHILDREN'S HOSPITAL MEDICAL CENTER (US) 2025-09-09 — — US claimed
CN-119464483-A Probe set for detecting variation of monogenic genetic disease, kit and application 苏州贝康医疗器械有限公司 2025-02-18 — — CN claimed
WO-2024251247-A1 ENGINEERED CELLS WITH ENHANCED TEAD PROTEIN TRANSCRIPTIONAL ACTIVITIES AND METHODS OF USE THEREOF NANJING LEGEND BIOTECH CO., LTD. (CN) 2024-12-12 — — WO claimed
WO-2024238182-A2 EPIGENETIC SIGNATURE OF T CELL AGING AND MALIGNANCY ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2024-11-21 — — WO claimed
WO-2024224296-A2 TARGETED PHARMACEUTICAL COMPOSITIONS TO TREAT NEUROLOGICAL CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-10-31 — — WO claimed
US-20240327927-A1 ACTIVE SURVEILLANCE AND RISK STRATIFICATION FOR PROSTATE CANCER IMMUNIS.AI, INC. 2024-10-03 — — US claimed
WO-2024206495-A2 ACTIVE SURVEILLANCE AND RISK STRATIFICATION FOR PROSTATE CANCER IMMUNIS.AI, INC. (US) 2024-10-03 — — WO claimed
EP-4153995-A2 DETECTION AND TREATMENT OF CONDITIONS CHARACTERIZED BY PERFUSION SHORTAGE Falcon Bioscience, LLC (US) 2023-03-29 — — EP claimed
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2023-03-23 — — US claimed
US-11579140-B2 Methods related to bronchial premalignant lesion severity and progression TRUSTEES OF BOSTON UNIVERSITY (US) 2023-02-14 — — US claimed
US-11485743-B2 Protein degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2022-11-01 — — US claimed
CN-109310727-B Conditionally active heterodimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2022-09-27 — — CN claimed
US-20220265657-A1 ADMINISTRATION METHOD AND DOSAGE REGIMEN FOR TREATMENT OF NEURODEGENERATIVE DISEASES USING TRAMETINIB AND MARKERS GENUV INC (KR) 2022-08-25 — — US claimed
US-20220234591-A1 GRIP STRENGTH SMART SLEEVES TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2022-07-28 — — US claimed
WO-2022103282-A1 NOVEL STEROID HORMONE LIGAND ASSAYS INSITUGEN LIMITED (NZ) 2022-05-19 — — WO claimed
WO-2022103283-A1 NOVEL STEROID HORMONE LIGAND ASSAYS INSITUGEN LIMITED (NZ) 2022-05-19 — — WO claimed
CN-110928670-B Workflow optimization method based on partial sequence adaptive genetic algorithm in cloud computing environment 浙江工商大学 2022-04-08 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485743-B2 Protein degraders and uses thereof MDM2, CUL1, PSMG3 CCNA2 3517/4885CDK2 1638/4885CCNA1 3366/4885
US-20230093080-A1 PROTEIN DEGRADERS AND USES THEREOF MDM2, CUL1, PSMG3 CCNA2 3517/4885CDK2 1638/4885CCNA1 3366/4885
US-12577609-B2 Methods for cell-type specific profiling to identify drug targets MYL12A, CELF2, RABL3 CCNA2 2969/4885CDK2 3756/4885CCNA1 3677/4885
US-20220265657-A1 ADMINISTRATION METHOD AND DOSAGE REGIMEN FOR TREATMENT OF NEURODEGENERATIVE DISEASES USING TRAMETINIB AND MARKERS PMP22, NGF, NTRK1 CCNA2 1664/4885CDK2 2406/4885CCNA1 1274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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