SCHEMBL29736049

SCHEMBL29736049

CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CCNA2 P20248 4/20 0.65
▸ CDK2 P24941 4/20 0.65
▸ CCNA1 P78396 3/20 0.65
▸ AGTR1 P30556 1/20 0.56
▸ AGTR2 P50052 1/20 0.56
▸ APLNR P35414 4/20 0.54
▸ CDK4 P11802 2/20 0.52
▸ CCND1 P24385 2/20 0.52
▸ PTH1R Q03431 4/20 0.52
▸ NPY1R P25929 1/20 0.52
▸ NPY2R P49146 1/20 0.52
▸ NPY4R P50391 1/20 0.52
▸ BACE1 P56817 1/20 0.52
▸ REN P00797 2/20 0.50
▸ VIPR1 P32241 2/20 0.50
▸ VIPR2 P41587 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372126 0.85 CCNA2 (0.61) CCNA2CDK2CCNA1AGTR1AGTR2
SCHEMBL29464255 0.83 PTH1R (0.55) CCNA2CDK2CCNA1PTH1R
SCHEMBL30122771 0.83 CCNA2 (0.64) CCNA2CDK2CCNA1AGTR1AGTR2
SCHEMBL29702256 0.81 CCNA2 (0.69) CCNA2CDK2CCNA1AGTR1AGTR2
SCHEMBL29358777 0.81 NPY1R (0.57) CCNA2CDK2CDK4CCND1NPY1R
SCHEMBL29393138 0.81 BACE1 (0.61) CCNA2CDK2AGTR1AGTR2CDK4
SCHEMBL29392502 0.81 BACE1 (0.61) CCNA2CDK2AGTR1AGTR2CDK4
SCHEMBL29419646 0.81 CCNA2 (0.58) CCNA2CDK2CCNA1APLNRPTH1R
SCHEMBL23083920 0.80 CCNA2 (0.58) CCNA2CDK2CCNA1AGTR1AGTR2
SCHEMBL30607220 0.78 BACE1 (0.65) CCNA2CDK2CCNA1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968583-B1 METHOD OF PRODUCING AN IMMUNOLIGAND/PAYLOAD CONJUGATE BY MEANS OF A SEQUENCE-SPECIFIC TRANSPEPTIDASE ENZYME NBE THERAPEUTICS AG (CH) 2025-06-04 — — EP disclosed
US-11986535-B2 Method of producing an immunoligand/payload conjugate NBE THERAPEUTICS AG (CH) 2024-05-21 — — US disclosed
US-20220378927-A1 METHOD OF PRODUCING AN IMMUNOLIGAND/PAYLOAD CONJUGATE NBE THERAPEUTICS AG (CH) 2022-12-01 — — US disclosed
US-11364301-B2 Method of producing an immunoligand/payload conjugate NBE-THERAPEUTICS AG (CH) 2022-06-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220378927-A1 METHOD OF PRODUCING AN IMMUNOLIGAND/PAYLOAD CONJUGATE DNPEP, FOLH1, ENGASE CCNA2 4041/4885CDK2 4800/4885CCNA1 4358/4885
US-11986535-B2 Method of producing an immunoligand/payload conjugate AGBL2, FOLH1, FCGR3B CCNA2 3642/4885CDK2 4663/4885CCNA1 4353/4885
US-11364301-B2 Method of producing an immunoligand/payload conjugate AGBL2, FOLH1, FCGR3B CCNA2 3642/4885CDK2 4663/4885CCNA1 4353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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