Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.45 |
| ▸ | CNR1 | P21554 | 8/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937263 | 0.89 | ALOX5 (0.52) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL2939513 | 0.84 | ALOX15 (0.43) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL2937933 | 0.83 | MKNK1 (0.43) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL2939499 | 0.82 | ALOX15 (0.44) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL2933993 | 0.82 | NQO1 (0.48) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL2931098 | 0.78 | CNR1 (0.44) | CNR2CNR1ALOX15TSHRALDH1A1 | |
| SCHEMBL2941045 | 0.78 | TSHR (0.41) | CNR2CNR1ALOX15TSHRALDH1A1 | |
| SCHEMBL2931222 | 0.77 | TDP1 (0.42) | ALOX15TSHRALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL2936687 | 0.77 | ALOX15 (0.54) | ALOX15TSHRALDH1A1HPGDALOX12 | |
| SCHEMBL5712441 | 0.77 | ALOX15 (0.36) | CNR2CNR1ALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | claimed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | disclosed |
| US-7033401-B2 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AG (DE) | 2006-04-25 | — | — | US | disclosed |
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | WELLA AKTIENGESELLSCHAFT (DE) | 2004-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147515-A1 | 3-Aminophenol derivatives substituted in the 2-position, and dyes containing these compounds | ALPP, TYR, RB1 | CNR2 1600/4885CNR1 1525/4885ALOX15 3697/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.