SCHEMBL29372811

SCHEMBL29372811

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nearest known ligand 0.64

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 3/20 0.64
OPRD1 P41143 3/20 0.64
OPRK1 P41145 1/20 0.64
BACE1 P56817 12/20 0.62
BACE2 Q9Y5Z0 6/20 0.62
KISS1R Q969F8 3/20 0.59
CTSD P07339 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30123741 0.94 BACE1 (0.59) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31538473 0.93 OPRM1 (0.61) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31510101 0.93 BACE1 (0.67) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31538474 0.92 OPRM1 (0.56) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29373148 0.92 BACE1 (0.60) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29375830 0.91 BACE1 (0.59) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31538481 0.91 BACE1 (0.57) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL31759060 0.89 GLP1R (0.60) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL29634680 0.88 BACE1 (0.64) OPRM1OPRD1OPRK1BACE1BACE2
SCHEMBL30312171 0.87 OPRM1 (0.55) OPRM1OPRD1OPRK1BACE1BACE2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP claimed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US claimed
WO-2025093774-A1 GLUCAGON-LIKE PEPTIDE 1 AGONISTS Constructive Biology Limited (GB) 2025-05-08 WO disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 CN disclosed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP OPRM1 4009/4885OPRD1 3405/4885OPRK1 2740/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP OPRM1 4009/4885OPRD1 3405/4885OPRK1 2740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.