SCHEMBL29375830

SCHEMBL29375830

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nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 11/20 0.59
BACE2 Q9Y5Z0 6/20 0.59
OPRD1 P41143 2/20 0.53
OPRM1 P35372 1/20 0.53
OPRK1 P41145 1/20 0.53
CTSD P07339 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373148 0.96 BACE1 (0.60) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL31538481 0.92 BACE1 (0.57) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL29372811 0.91 OPRM1 (0.64) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL29728788 0.90 OPRM1 (0.55) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL31344055 0.90 OPRD1 (0.60) BACE1BACE2OPRD1
SCHEMBL29375272 0.88 IL1RN (0.54) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL30123741 0.88 BACE1 (0.59) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL2463657 0.88 TFPI (0.56) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL30124163 0.88 IL1RN (0.52) BACE1BACE2OPRD1OPRM1OPRK1
SCHEMBL31538473 0.87 OPRM1 (0.61) BACE1BACE2OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP claimed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US claimed
WO-2025093774-A1 GLUCAGON-LIKE PEPTIDE 1 AGONISTS Constructive Biology Limited (GB) 2025-05-08 WO disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 CN disclosed
EP-4196495-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP Pharma GmbH (CH) 2023-06-21 EP disclosed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US disclosed
WO-2022034062-A1 EXENDIN-4 PEPTIDE ANALOGUES TXP PHARMA AG (CH) 2022-02-17 WO disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP BACE1 569/4885BACE2 611/4885OPRD1 3405/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP BACE1 569/4885BACE2 611/4885OPRD1 3405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.