Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.80 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.73 |
| ▸ | CNR2 | P34972 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.71 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | PTGES | O14684 | 1/20 | 0.71 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.71 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.71 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.71 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739299 | 0.89 | PTGS2 (1.00) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL11615788 | 0.89 | PTGS2 (0.73) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL29454436 | 0.88 | PTGS2 (0.84) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL31262996 | 0.88 | PTGS2 (0.72) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL11405394 | 0.88 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL2739339 | 0.87 | PTGS2 (0.73) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL150556 | 0.86 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL150555 | 0.86 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL11827594 | 0.86 | PTGS2 (0.74) | PTGS2AKR1C3CNR2PTGS1GLO1 | |
| SCHEMBL11092811 | 0.85 | PTGS2 (0.88) | PTGS2AKR1C3CNR2PTGS1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4104902-B1 | COMPOUNDS AND MEDICAMENTS USING SAME | IRIMAJIRI THERAPEUTICS INC (JP) | 2026-05-27 | — | — | EP | disclosed |
| CN-122012611-A | DNA nanostructure carrier, DNA nano medicine and application thereof | 北京君全智药生物科技有限公司 | 2026-05-12 | — | — | CN | disclosed |
| EP-4319723-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BACTERIA | Evelo Biosciences, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| US-11780841-B2 | 3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-c]pyridine compounds and medicaments using same | IRIMAJIRI THERAPEUTICS INC. (JP) | 2023-10-10 | — | — | US | disclosed |
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | disclosed |
| US-20230279034-A1 | COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-09-07 | — | — | US | disclosed |
| CN-116521015-A | Baseline processing method, baseline processing device, electronic equipment and storage medium | 北京奕斯伟计算技术股份有限公司 | 2023-08-01 | — | — | CN | disclosed |
| US-20230192708-A1 | 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES | IDORSIA PHARMACEUTICALS LTD (CH) | 2023-06-22 | — | — | US | disclosed |
| EP-4190864-A1 | COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-06-07 | — | — | EP | disclosed |
| EP-4162059-A1 | COMPOSITIONS FOR DRG-SPECIFIC REDUCTION OF TRANSGENE EXPRESSION | The Trustees of The University of Pennsylvania (US) | 2023-04-12 | — | — | EP | disclosed |
| EP-4133107-A1 | METHODS OF DIAGNOSING CANCER AND PREDICTING RESPONSIVENESS TO THERAPY | Yeda Research and Development Co. Ltd (IL) | 2023-02-15 | — | — | EP | disclosed |
| EP-4104902-A1 | COMPOUND AND DRUG CONTAINING SAME | Oita University Institute of Advanced Medicine, Inc. (JP) | 2022-12-21 | — | — | EP | disclosed |
| EP-3737684-B1 | 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-11-16 | — | — | EP | disclosed |
| WO-2022217030-A1 | PHARMACEUTICAL COMPOSITION CONTAINING BACTERIA | EVELO BIOSCIENCES, INC. (US) | 2022-10-13 | — | — | WO | disclosed |
| CN-115052661-A | Compound and drug using the same | 株式会社大分大学先端医学研究所 | 2022-09-13 | — | — | CN | disclosed |
| CN-112839944-B | Compounds and methods for treating rabies | 株式会社大分大学先端医学研究所 | 2022-08-05 | — | — | CN | disclosed |
| US-20220194942-A1 | 3,6-METHANO-1H-PYRROLO[3,2-b]PYRIDINE AND 3,6-METHANO-1H-PYRROLO[3,2-c]PYRIDINE COMPOUNDS AND MEDICAMENTS USING SAME | IRIMAJIRI THERAPEUTICS INC. (JP) | 2022-06-23 | — | — | US | disclosed |
| EP-2694505-B1 | HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2022-04-27 | — | — | EP | disclosed |
| US-11292794-B2 | 3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-C]pyridine compounds and medicaments using same | OITA UNIVERSITY INSTITUTE OF ADVANCED MEDICINE, INC. (JP) | 2022-04-05 | — | — | US | disclosed |
| EP-3948274-A1 | METHODS FOR PHOTOIMMUNOTHERAPY AND RELATED BIOMARKERS | Rakuten Medical, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11292794-B2 | 3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-C]pyridine compounds and medicaments using same | AVPR1B, F12, SDHB | PTGS2 2626/4885AKR1C3 1504/4885CNR2 814/4885 |
| US-11780841-B2 | 3,6-methano-1H-pyrrolo[3,2-b]pyridine and 3,6-methano-1H-pyrrolo[3,2-c]pyridine compounds and medicaments using same | AVPR1B, AVPR2, F12 | PTGS2 1584/4885AKR1C3 1312/4885CNR2 389/4885 |
| US-20230279034-A1 | COMPOUND | BAK1, ALOX12, CYC1 | PTGS2 197/4885AKR1C3 29/4885CNR2 1063/4885 |
| US-20220194942-A1 | 3,6-METHANO-1H-PYRROLO[3,2-b]PYRIDINE AND 3,6-METHANO-1H-PYRROLO[3,2-c]PYRIDINE COMPOUNDS AND MEDICAMENTS USING SAME | AVPR1B, AVPR2, F12 | PTGS2 1584/4885AKR1C3 1312/4885CNR2 389/4885 |
| US-20230192708-A1 | 2,4,6,7-TETRAHYDRO-PYRAZOLO[4,3-D]PYRIMIDIN-5-ONE DERIVATIVES AND RELATED COMPOUNDS AS C5A RECEPTOR MODULATORS FOR TREATING VASCULITIS AND INFLAMMATORY DISEASES | C3AR1, C5AR1, C5AR2 | PTGS2 740/4885AKR1C3 125/4885CNR2 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.