Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 4/20 | 0.73 |
| ▸ | CCR8 | P51685 | 4/20 | 0.73 |
| ▸ | CCR5 | P51681 | 3/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.73 |
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14473534 | 0.90 | KDM4E (0.67) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL3423342 | 0.90 | CCR1 (0.64) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL17776912 | 0.86 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL12681427 | 0.86 | CCR1 (0.59) | CCR1CCR8CCR5HDAC6METAP2 | |
| Abametapir SCHEMBL351152 | 0.85 | CCR1 (1.00) | CCR1CCR8CCR5HDAC6METAP2 | |
| Abametapir SCHEMBL29374261 | 0.85 | CCR1 (1.00) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL13962549 | 0.84 | CCR1 (0.52) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL13013805 | 0.82 | KDM4E (0.55) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL14804379 | 0.80 | CCR1 (0.89) | CCR1CCR8CCR5HDAC6METAP2 | |
| SCHEMBL564428 | 0.80 | CCR1 (0.70) | CCR1CCR8CCR5HDAC6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053642-A1 | CONTROLLED (CO)POLYMERISATION WITH N-HETEROCYCLES METAL COMPLEX SYSTEMS | SCHUBERT ULRICH S (DE) | 2000-09-14 | — | — | WO | disclosed |