Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 10/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6714735 | 1.00 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6637762 | 0.87 | EED (0.50) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22466030 | 0.86 | KMT2A (0.63) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2600447 | 0.84 | EED (0.72) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL10535845 | 0.82 | EED (0.70) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10535865 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30101805 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10534823 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL702928 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29836510 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-3946599-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | Neuropore Therapies, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |