Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 10/20 | 0.59 |
| ▸ | GRIN3B | O60391 | 10/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 10/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 10/20 | 0.59 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.59 |
| ▸ | GRIN2C | Q14957 | 10/20 | 0.59 |
| ▸ | GRIN3A | Q8TCU5 | 10/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375196 | 1.00 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6637762 | 0.87 | EED (0.50) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22466030 | 0.86 | KMT2A (0.63) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2600447 | 0.84 | EED (0.72) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| Hydrochloric Acid SCHEMBL10535845 | 0.82 | EED (0.70) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10535865 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30101805 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL10534823 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL702928 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29836510 | 0.81 | EED (0.64) | EEDGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220298155-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2022-09-22 | — | — | US | disclosed |
| US-11299487-B2 | Compounds and compositions as modulators of TLR signaling | NEUROPORE THERAPIES, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20200308163-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | NEUROPORE THERAPIES, INC. (US) | 2020-10-01 | — | — | US | disclosed |
| CN-101759637-B | N-aryl-3,4-dihydro-isoquinoline salt and application thereof in preparing acaricidal and antibiotic medicament | NORTHWEST A & F UNIVERSITY (CN) | 2012-02-01 | — | — | CN | disclosed |
| CN-101759637-A | N-aryl-3,4-dihydro-isoquinoline salt and application thereof in preparing acaricidal and antibiotic medicament | UNIV NORTHWEST A&F | 2010-06-30 | — | — | CN | disclosed |
| CN-1555260-A | Aminoalkyl-substituted aromatic bicyclic compounds, process for their preparation and their use as pharmaceuticals | ���ĵ�˹ҩ��¹�����˾ | 2004-12-15 | — | — | CN | disclosed |
| US-20040198731-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040198732-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040198733-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-10-07 | — | — | US | disclosed |
| US-20040192693-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-30 | — | — | US | disclosed |
| US-20030212070-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220298155-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | TLR3, TLR6, TLR4 | EED 3422/4885GRIN2D 825/4885GRIN3B 220/4885 |
| US-20030212070-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | EED 2416/4885GRIN2D 454/4885GRIN3B 714/4885 |
| US-20200308163-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF TLR SIGNALING | TLR3, TLR6, TLR4 | EED 3422/4885GRIN2D 825/4885GRIN3B 220/4885 |
| US-20040192693-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | EED 2416/4885GRIN2D 454/4885GRIN3B 714/4885 |
| US-20040198731-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | EED 2416/4885GRIN2D 454/4885GRIN3B 714/4885 |
| US-20040198733-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | EED 2416/4885GRIN2D 454/4885GRIN3B 714/4885 |
| US-20040198732-A1 | Aminoalkyl-substituted aromatic bicyclic compounds, methods for their preparation and their use as pharmaceuticals | PER2, CNR2, DDC | EED 2416/4885GRIN2D 454/4885GRIN3B 714/4885 |
| US-11299487-B2 | Compounds and compositions as modulators of TLR signaling | TLR3, TLR6, TLR4 | EED 2753/4885GRIN2D 684/4885GRIN3B 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.