Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.88 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | TYR | P14679 | 3/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288230 | 0.86 | PTPN1 (0.81) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL30631321 | 0.85 | PTPN1 (0.81) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL26112000 | 0.85 | PTPN1 (0.81) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL5614193 | 0.85 | PTPN1 (1.00) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL29375421 | 0.85 | PTPN1 (1.00) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL29516022 | 0.84 | PTPN1 (0.82) | PTPN1HSP90AA1ACHETYRKDM4E | |
| SCHEMBL12866209 | 0.84 | PTPN1 (0.82) | PTPN1HSP90AA1ACHETYRKDM4E | |
| SCHEMBL31290568 | 0.80 | PTPN1 (0.72) | PTPN1HSP90AA1ACHETYR | |
| SCHEMBL30631316 | 0.79 | PTPN1 (0.87) | PTPN1HSP90AA1ACHETYRPDCD1 | |
| SCHEMBL8081861 | 0.79 | PTPN1 (0.87) | PTPN1HSP90AA1ACHETYRPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| CN-115721671-A | Method for extracting and separating effective components of liquorice root in full-industrial-chain cooperation manner | 李玉山 | 2023-03-03 | — | — | CN | claimed |
| US-20250319141-A1 | USE OF MICROBIOME FOR ASSESSMENT AND TREATMENT OF OBESITY AND TYPE 2 DIABETES | UNIV HONG KONG CHINESE (CN) | 2025-10-16 | — | — | US | disclosed |
| US-20250093345-A1 | Optical biomodule for detection of diseases at an early onset | MAZED MOHAMMAD A (US) | 2025-03-20 | — | — | US | disclosed |
| US-12135286-B1 | Optical biomodule for detection of diseases at an early onset | MAZED MOHAMMAD A (US) | 2024-11-05 | — | — | US | disclosed |
| CN-117529548-A | Use of microbiome for assessing and treating obesity and type 2 diabetes | 香港中文大学 | 2024-02-06 | — | — | CN | disclosed |
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11747279-B2 | Optical biomodule for detection of diseases at an early onset | MAZED MOHAMMAD A (US) | 2023-09-05 | — | — | US | disclosed |
| CN-115721671-A | Method for extracting and separating effective components of liquorice root in full-industrial-chain cooperation manner | 李玉山 | 2023-03-03 | — | — | CN | disclosed |
| WO-2022206895-A1 | USE OF MICROBIOME FOR ASSESSMENT AND TREATMENT OF OBESITY AND TYPE 2 DIABETES | THE CHINESE UNIVERSITY OF HONG KONG (CN) | 2022-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016777-A1 | COMPOUNDS AND METHODS FOR TREATING VIRAL INFECTIONS | THPO, SERPINB1, SERPINC1 | PTPN1 1318/4885HSP90AA1 1340/4885ACHE 4241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.