SCHEMBL29375430

SCHEMBL29375430

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nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MME P08473 2/20 0.46
ENPEP Q07075 14/20 0.43
CTSC P53634 1/20 0.42
BACE1 P56817 1/20 0.40
BACE2 Q9Y5Z0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375970 1.00 MME (0.46) MMEENPEPCTSCBACE1BACE2
SCHEMBL30906339 0.94 MME (0.41) MMECTSCBACE1
SCHEMBL30123289 0.90 ENPEP (0.48) ENPEP
SCHEMBL30053678 0.88 MME (0.50) MMEENPEPCTSC
SCHEMBL29973181 0.88 BACE1 (0.48) ENPEPBACE1
SCHEMBL2198060 0.87 CASP3 (0.36) ENPEPBACE1BACE2
SCHEMBL29371327 0.87 MME (0.50) MMEENPEP
SCHEMBL30165201 0.87 ENPEP (0.43) ENPEPCTSCBACE1BACE2
SCHEMBL30011153 0.87 MME (0.42) MMEENPEPCTSC
SCHEMBL31039950 0.86 BACE1 (0.44) MMECTSCBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP MME 1189/4885ENPEP 262/4885CTSC 26/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP MME 1189/4885ENPEP 262/4885CTSC 26/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.