SCHEMBL29376413

SCHEMBL29376413

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 1/20 0.56
▸ OPRM1 P35372 6/20 0.55
▸ OPRD1 P41143 5/20 0.55
▸ OPRK1 P41145 5/20 0.55
▸ NPBWR1 P48145 11/20 0.53
▸ NPY1R P25929 1/20 0.51
▸ NPY2R P49146 1/20 0.51
▸ NPY4R P50391 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34468124 0.96 TFPI (0.60) TFPIOPRM1OPRD1OPRK1NPBWR1
SCHEMBL29375967 0.94 TFPI (0.59) TFPIOPRM1OPRD1OPRK1NPBWR1
SCHEMBL29590452 0.93 OPRM1 (0.55) TFPIOPRM1OPRD1OPRK1NPY1R
SCHEMBL30721576 0.93 TFPI (0.61) TFPIOPRM1OPRD1OPRK1NPBWR1
SCHEMBL31614432 0.92 OPRD1 (0.56) OPRM1OPRD1OPRK1NPY1RNPY4R
SCHEMBL31614421 0.92 OPRD1 (0.57) OPRM1OPRD1OPRK1NPY1RNPY2R
SCHEMBL31672190 0.91 NPY4R (0.60) OPRK1NPY1RNPY2RNPY4R
SCHEMBL31614425 0.90 OPRD1 (0.56) OPRM1OPRD1OPRK1NPY1RNPY2R
SCHEMBL29525489 0.90 TFPI (0.63) TFPIOPRM1OPRD1OPRK1NPBWR1
SCHEMBL30861917 0.90 TFPI (0.61) TFPIOPRM1OPRD1OPRK1NPBWR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US claimed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 — — US claimed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 — — US claimed
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2026-04-16 — — US disclosed
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs ENZENE BIOSCIENCES LIMITED (IN) 2026-04-14 — — US disclosed
US-20250206798-A1 INSULIN CONJUGATES SANOFI SA (FR) 2025-06-26 — — US disclosed
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-06-12 — — US disclosed
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES Nanjing Finepeptide Biopharmaceutical Co.,Ltd (CN) 2024-05-09 — — US disclosed
WO-2024068827-A1 METHOD FOR PREPARING LIRAGLUTIDE BACHEM HOLDING AG (CH) 2024-04-04 — — WO disclosed
CN-112912390-B GLP-1 analogues and methods of preparation 北京费森尤斯卡比医药有限公司 2023-12-15 — — CN disclosed
EP-3864032-B1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES FRESENIUS KABI IPSUM S R L (IT) 2022-11-30 — — EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 — — US disclosed
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS ENZENE BIOSCIENCES LIMITED (IN) 2022-05-19 — — US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150423-A1 GLP-1 ANALOGUE-MODIFIED DIMERS WITH DIFFERENT CONFIGURATIONS, PREPARATION METHOD THEREOF, AND APPLICATION THEREOF IN TREATMENT OF TYPE II DIABETES GLP1R, IAPP, GCG TFPI 864/4885OPRM1 2449/4885OPRD1 2268/4885
US-20260103498-A1 METHOD FOR PREPARING LIRAGLUTIDE GLP1R, IAPP, VIP TFPI 1087/4885OPRM1 2309/4885OPRD1 3623/4885
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP TFPI 525/4885OPRM1 4009/4885OPRD1 3405/4885
US-20220153804-A1 PROCESS OF PREPARATION OF GLUCAGON-LIKE PEPTIDE-1 (GLP-1) RECEPTOR AGONISTS AND THEIR ANALOGS GLP1R, GIPR, GCGR TFPI 3297/4885OPRM1 2254/4885OPRD1 1916/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP TFPI 525/4885OPRM1 4009/4885OPRD1 3405/4885
US-12600759-B2 Process of preparation of glucagon-like peptide-1 (GLP-1) receptor agonists and their analogs GLP1R, GIPR, GCG TFPI 2018/4885OPRM1 490/4885OPRD1 408/4885
US-20250188115-A1 PROCESS FOR PREPARING A GLUCAGON-LIKE PEPTIDE GLP1R, IAPP, GCG TFPI 874/4885OPRM1 4237/4885OPRD1 4401/4885
US-20250206798-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R TFPI 1891/4885OPRM1 4488/4885OPRD1 4779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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