Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.61 |
| ▸ | ERAP2 | Q6P179 | 8/20 | 0.59 |
| ▸ | ECE1 | P42892 | 5/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | IL1RN | P18510 | 8/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.54 |
| ▸ | MMP2 | P08253 | 2/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30307309 | 0.96 | OPRM1 (0.62) | OPRM1OPRD1ERAP2ECE1NPBWR1 | |
| SCHEMBL30576711 | 0.96 | OPRM1 (0.68) | OPRM1OPRD1ERAP2NPBWR1IL1RN | |
| SCHEMBL30576704 | 0.96 | OPRM1 (0.68) | OPRM1OPRD1ERAP2NPBWR1IL1RN | |
| SCHEMBL30052459 | 0.94 | ECE1 (0.61) | OPRM1OPRD1ERAP2ECE1IL1RN | |
| SCHEMBL29794167 | 0.93 | OPRM1 (0.62) | OPRM1OPRD1ERAP2ECE1MMP2 | |
| SCHEMBL29872607 | 0.93 | OPRM1 (0.62) | OPRM1OPRD1ERAP2ECE1MMP2 | |
| SCHEMBL9868659 | 0.92 | OPRM1 (0.66) | OPRM1OPRD1ECE1 | |
| SCHEMBL29391520 | 0.92 | OPRM1 (0.66) | OPRM1OPRD1ECE1 | |
| Trifluoroacetic Acid SCHEMBL30576699 | 0.92 | OPRD1 (0.64) | OPRM1OPRD1ERAP2NPBWR1IL1RN | |
| SCHEMBL30538857 | 0.91 | ECE1 (0.57) | OPRM1OPRD1ERAP2ECE1NPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851468-B2 | Treatment of neurological diseases | UNIVERSITY OF LANCASTER (GB) | 2023-12-26 | — | — | US | disclosed |
| US-20220033457-A1 | TREATMENT OF NEUROLOGICAL DISEASES | UNIVERSITY OF LANCASTER (GB) | 2022-02-03 | — | — | US | disclosed |