SCHEMBL30307309

SCHEMBL30307309

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)O

nearest known ligand 0.62

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRM1 P35372 2/20 0.62
▸ OPRD1 P41143 2/20 0.62
▸ NPBWR1 P48145 9/20 0.60
▸ ERAP2 Q6P179 6/20 0.56
▸ ECE1 P42892 2/20 0.54
▸ IL1RN P18510 6/20 0.53
▸ ERAP1 Q9NZ08 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376430 0.96 OPRM1 (0.61) OPRM1OPRD1NPBWR1ERAP2ECE1
SCHEMBL30538857 0.95 ECE1 (0.57) OPRM1OPRD1NPBWR1ERAP2ECE1
SCHEMBL30576704 0.92 OPRM1 (0.68) OPRM1OPRD1NPBWR1ERAP2IL1RN
SCHEMBL30576711 0.92 OPRM1 (0.68) OPRM1OPRD1NPBWR1ERAP2IL1RN
SCHEMBL30052459 0.91 ECE1 (0.61) OPRM1OPRD1ERAP2ECE1IL1RN
SCHEMBL29794167 0.89 OPRM1 (0.62) OPRM1OPRD1ERAP2ECE1
SCHEMBL29872607 0.89 OPRM1 (0.62) OPRM1OPRD1ERAP2ECE1
SCHEMBL9868659 0.89 OPRM1 (0.66) OPRM1OPRD1ECE1
SCHEMBL29391520 0.89 OPRM1 (0.66) OPRM1OPRD1ECE1
Trifluoroacetic Acid SCHEMBL30576699 0.89 OPRD1 (0.64) OPRM1OPRD1NPBWR1ERAP2IL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4171662-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES Antaros Medical AB (SE) 2023-05-03 — — EP claimed
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 — — US claimed
EP-4171662-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES Antaros Medical AB (SE) 2023-05-03 — — EP disclosed
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES ANTAROS MEDICAL AB (SE) 2023-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230127047-A1 SELECTIVE GIP RECEPTOR AGONISTS COMPRISING A CHELATING MOIETY FOR IMAGING AND THERAPY PURPOSES GIPR, GRPR, GLP1R OPRM1 506/4885OPRD1 1019/4885NPBWR1 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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