Demoxytocin

Demoxytocin

SCHEMBL29376547

CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 6/20 0.88
▸ OXTR P30559 15/20 0.88
▸ AVPR2 P30518 5/20 0.88
▸ AVPR1B P47901 5/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demoxytocin SCHEMBL38443 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Demoxytocin SCHEMBL38442 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL28086558 0.97 OXTR (0.93) AVPR1AOXTRAVPR2AVPR1B
Oxytocin Trisulfide SCHEMBL30712243 0.97 AVPR1A (0.86) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511632 0.95 AVPR1A (0.80) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL22333521 0.95 AVPR1A (0.79) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511860 0.94 OXTR (0.81) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511596 0.94 AVPR1A (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL29048 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL21527573 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3242676-B1 MAGNESIUM-CONTAINING OXYTOCIN FORMULATIONS AND METHODS OF USE TONIX Pharmaceuticals Holding Corp (US) 2023-10-04 — — EP claimed
WO-2022200568-A1 TREATMENT OF DYSPHAGIA OT4B (FR) 2022-09-29 — — WO claimed
US-20260053883-A1 OXYTOCIN COMPOSITIONS FOR TREATMENT OF VISUAL SNOW SYNDROME MASKBEGONE LLC (US) 2026-02-26 — — US disclosed
WO-2025245322-A1 OXYTOCIN-BASED THERAPEUTICS TO IMPROVE COGNITIVE CONTROL IN INDIVIDUALS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER THE GENERAL HOSPITAL CORPORATION (US) 2025-11-27 — — WO disclosed
US-12466855-B2 Labeled oxytocin and method of manufacture and use TONIX PHARMA LIMITED (IE) 2025-11-11 — — US disclosed
US-20250319153-A1 MAGNESIUM-CONTAINING OXYTOCIN FORMULATIONS AND METHODS OF USE TONIX PHARMA LTD (IE) 2025-10-16 — — US disclosed
US-20250255930-A1 METHODS OF TREATMENT OF TINNITUS USING DERIVATIVES OF OXYTOCIN MASKBEGONE LLC (US) 2025-08-14 — — US disclosed
CN-120091810-A Methods and highly bioavailable permeable compounds for treating viral diseases 基里尔·迪丹克 2025-06-03 — — CN disclosed
EP-4541348-A2 MAGNESIUM-CONTAINING OXYTOCIN FORMULATIONS AND METHODS OF USE Tonix Pharma Limited (IE) 2025-04-23 — — EP disclosed
US-12156897-B2 Magnesium-containing oxytocin formulations and methods of use TONIX PHARMA LIMITED (IE) 2024-12-03 — — US disclosed
EP-3442560-B1 MAGNESIUM-CONTAINING OXYTOCIN FORMULATIONS AND METHODS OF USE TONIX PHARMA LTD (IE) 2024-11-20 — — EP disclosed
CN-109414476-B Magnesium-containing oxytocin formulations and methods of use 三叉神经股份公司 2023-01-31 — — CN disclosed
CN-115647329-A Solution method for reducing invasive pores in aluminum alloy casting 安徽博煊铸造有限公司 2023-01-31 — — CN disclosed
CN-109963553-B Oral delivery vehicle 费尔廷制药公司 2022-11-22 — — CN disclosed
WO-2022200568-A1 TREATMENT OF DYSPHAGIA OT4B (FR) 2022-09-29 — — WO disclosed
CN-109952092-B Tablet comprising separate binder and erythritol 费尔廷制药公司 2022-08-23 — — CN disclosed
US-11389473-B2 Magnesium-containing oxytocin formulations and methods of use TONIX PHARMACEUTICALS HOLDING CORP. (US) 2022-07-19 — — US disclosed
EP-4021410-A1 OXYTOCIN COMPOSITIONS FOR TREATMENT OF TINNITUS New York University (US) 2022-07-06 — — EP disclosed
US-11266711-B2 Oxytocin compositions and methods of use ELGAN PHARMA LTD (IL) 2022-03-08 — — US disclosed
US-11241477-B2 Oxytocin compositions for treatment of tinnitus NEW YORK UNIVERSITY (US) 2022-02-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053883-A1 OXYTOCIN COMPOSITIONS FOR TREATMENT OF VISUAL SNOW SYNDROME OXTR, AVPR2, AVPR1B AVPR1A 4/4885OXTR 1/4885AVPR2 2/4885
US-12466855-B2 Labeled oxytocin and method of manufacture and use OXTR, AVPR1A, AVPR1B AVPR1A 2/4885OXTR 1/4885AVPR2 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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