Demoxytocin

Demoxytocin

SCHEMBL38442

CC[C@H](C)[C@@H]1NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CCSSC[C@@H](C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(N)=O)NC1=O

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 6/20 0.88
▸ OXTR P30559 15/20 0.88
▸ AVPR2 P30518 5/20 0.88
▸ AVPR1B P47901 5/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demoxytocin SCHEMBL38443 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Demoxytocin SCHEMBL29376547 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL28086558 0.97 OXTR (0.93) AVPR1AOXTRAVPR2AVPR1B
Oxytocin Trisulfide SCHEMBL30712243 0.97 AVPR1A (0.86) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511632 0.95 AVPR1A (0.80) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL22333521 0.95 AVPR1A (0.79) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511860 0.94 OXTR (0.81) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511596 0.94 AVPR1A (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL29048 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL21527573 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 773 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245322-A1 OXYTOCIN-BASED THERAPEUTICS TO IMPROVE COGNITIVE CONTROL IN INDIVIDUALS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER THE GENERAL HOSPITAL CORPORATION (US) 2025-11-27 — — WO claimed
EP-4313106-B1 TREATMENT OF DYSPHAGIA OT4B (FR) 2025-01-15 — — EP claimed
US-20240277624-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS NANEXA AB (SE) 2024-08-22 — — US claimed
US-20240197813-A1 TREATMENT OF DYSPHAGIA CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (FR) 2024-06-20 — — US claimed
EP-4351529-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS Nanexa AB (SE) 2024-04-17 — — EP claimed
US-20230381267-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE 2023-11-30 — — US claimed
EP-4221834-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME Baylor College of Medicine (US) 2023-08-09 — — EP claimed
WO-2022258985-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS NANEXA AB (SE) 2022-12-15 — — WO claimed
WO-2022073008-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE (US) 2022-04-07 — — WO claimed
US-20210346621-A1 INTRANASAL ADMINISTRATION Optinose, Inc. 2021-11-11 — — US claimed
WO-2003039479-A2 POLYMERIC THIOL-LINKED PRODRUGS ENZON, INC. (US) 2003-05-15 — — WO claimed
US-20020193442-A1 Method and compositions for the treatment or amelioration of female sexual dysfunction Parteq Innovations (CA) 2002-12-19 — — US claimed
US-20020165122-A1 Method and compositions for the treatment or amelioration of female sexual dysfunction QUEEN'S UNIVERSITY AT KINGSTON (CA) 2002-11-07 — — US claimed
EP-1089736-A2 METHOD AND COMPOSITIONS FOR THE TREATMENT OR AMELIORATION OF FEMALE SEXUAL DYSFUNCTION QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-04-11 — — EP claimed
EP-1082118-A2 METHODS FOR THE NORMALIZATION OF SEXUAL RESPONSE AND AMELIORATION OF LONG TERM GENITAL TISSUE DEGRADATION QUEEN'S UNIVERSITY AT KINGSTON (CA) 2001-03-14 — — EP claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 — — EP claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 — — WO claimed
WO-1999066909-A2 METHOD AND COMPOSITIONS FOR THE TREATMENT OR AMELIORATION OF FEMALE SEXUAL DYSFUNCTION UNIV KINGSTON (CA) 1999-12-29 — — WO claimed
WO-1999062502-A2 METHODS FOR THE NORMALIZATION OF SEXUAL RESPONSE AND AMELIORATION OF LONG TERM GENITAL TISSUE DEGRADATION QUEEN'S UNIVERSITY AT KINGSTON (CA) 1999-12-09 — — WO claimed
US-3943246-A ADMINISTERING OXYTOCIN OR DESAMINO-OXYTOCIN TO TREAT MALE IMPOTENCY SANDOZ LTD. (CH) 1976-03-09 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165122-A1 Method and compositions for the treatment or amelioration of female sexual dysfunction OXTR, GNRHR, VIPR2 AVPR1A 86/4885OXTR 1/4885AVPR2 42/4885
US-20240197813-A1 TREATMENT OF DYSPHAGIA OXTR, GRPR, NTSR2 AVPR1A 22/4885OXTR 1/4885AVPR2 14/4885
US-20020193442-A1 Method and compositions for the treatment or amelioration of female sexual dysfunction GNRHR, LHCGR, FSHR AVPR1A 91/4885OXTR 4/4885AVPR2 54/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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