Demoxytocin

Demoxytocin

SCHEMBL38443

CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCSSCC(C(=O)N2CCCC2C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ AVPR1A P37288 6/20 0.88
▸ OXTR P30559 15/20 0.88
▸ AVPR2 P30518 5/20 0.88
▸ AVPR1B P47901 5/20 0.88

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demoxytocin SCHEMBL29376547 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Demoxytocin SCHEMBL38442 1.00 AVPR1A (0.88) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL28086558 0.97 OXTR (0.93) AVPR1AOXTRAVPR2AVPR1B
Oxytocin Trisulfide SCHEMBL30712243 0.97 AVPR1A (0.86) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511632 0.95 AVPR1A (0.80) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL22333521 0.95 AVPR1A (0.79) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511860 0.94 OXTR (0.81) AVPR1AOXTRAVPR2AVPR1B
SCHEMBL15511596 0.94 AVPR1A (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL29048 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B
Oxytocin SCHEMBL21527573 0.94 OXTR (1.00) AVPR1AOXTRAVPR2AVPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245322-A1 OXYTOCIN-BASED THERAPEUTICS TO IMPROVE COGNITIVE CONTROL IN INDIVIDUALS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER THE GENERAL HOSPITAL CORPORATION (US) 2025-11-27 — — WO claimed
EP-4313106-B1 TREATMENT OF DYSPHAGIA OT4B (FR) 2025-01-15 — — EP claimed
US-20240277624-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS NANEXA AB (SE) 2024-08-22 — — US claimed
US-20240197813-A1 TREATMENT OF DYSPHAGIA CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE (FR) 2024-06-20 — — US claimed
EP-4351529-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS Nanexa AB (SE) 2024-04-17 — — EP claimed
US-20230381267-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE 2023-11-30 — — US claimed
EP-4221834-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME Baylor College of Medicine (US) 2023-08-09 — — EP claimed
WO-2022258985-A1 NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS NANEXA AB (SE) 2022-12-15 — — WO claimed
WO-2022073008-A1 OXYTOCIN TREATMENT FOR HYPERMOBILE EHLERS-DANLOS SYNDROME BAYLOR COLLEGE OF MEDICINE (US) 2022-04-07 — — WO claimed
US-20210346621-A1 INTRANASAL ADMINISTRATION Optinose, Inc. 2021-11-11 — — US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 — — US claimed
US-20100035805-A1 NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION OPTINOSE AS (NO) 2010-02-11 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 — — EP claimed
WO-2007141541-A1 INTRANASAL ADMINISTRATION OPTINOSE AS (NO) 2007-12-13 — — WO claimed
WO-2007125318-A1 NON-AQUEOUS LIQUID FORMULATION FOR NASAL OR BUCCAL ADMINISTRATION OPTINOSE AS (NO) 2007-11-08 — — WO claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 — — WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 — — US claimed
US-20050048164-A1 Chewing gum core overcoated with active powder materials containing anseptics, cooling compound, flavor intensifier, sweetening , enzyme, drug STAHL BRONISLAW-JAN (DK) 2005-03-03 — — US claimed
EP-1495681-A2 A coated chewing gum, a method for preparation thereof and the use of one or more active substances in the coating DANDY A/S (DK) 2005-01-12 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197813-A1 TREATMENT OF DYSPHAGIA OXTR, GRPR, NTSR2 AVPR1A 22/4885OXTR 1/4885AVPR2 14/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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