SCHEMBL29377477

SCHEMBL29377477

Brc1ccc(Oc2ccc(Br)cc2)cc1.[P]

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.70
CYP2A6 P11509 1/20 0.53
MAOA P21397 1/20 0.48
MAOB P27338 1/20 0.48
LTA4H P09960 3/20 0.47
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP14 P50281 1/20 0.45
CA14 Q9ULX7 1/20 0.45
PTGS2 P35354 1/20 0.45
ALDH1A1 P00352 4/20 0.45
TSHR P16473 3/20 0.45
CYP3A4 P08684 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ESR1 P03372 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3842527 0.97 MAPT (0.74) MAPTCYP2A6MAOAMAOBLTA4H
SCHEMBL391385 0.97 MAPT (0.74) MAPTCYP2A6MAOAMAOBLTA4H
SCHEMBL3843978 0.97 MAPT (0.74) MAPTCYP2A6MAOAMAOBLTA4H
Phosphine SCHEMBL23732402 0.93 MAPT (0.70) MAPTCYP2A6MAOAMAOBLTA4H
Hydrogen Sulfide SCHEMBL8755564 0.90 MAPT (0.67) MAPTCYP2A6MAOAMAOBLTA4H
SCHEMBL6268474 0.88 MAPT (0.64) MAPTCYP2A6MAOAMAOBLTA4H
SCHEMBL20565541 0.85 MAPT (0.61) MAPTCYP2A6MAOAMAOBLTA4H
SCHEMBL314422 0.85 LTA4H (0.67) MAPTMAOALTA4HCA2CA9
SCHEMBL18105336 0.85 LTA4H (0.67) MAPTMAOALTA4HCA2CA9
SCHEMBL1136688 0.83 LTA4H (0.63) MAPTMAOALTA4HCA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114031639-A Preparation method of biphosphonate with P-O-C-P structure 烟台大学 2022-02-11 CN claimed