Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.56 |
| ▸ | BAX | Q07812 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18105336 | 1.00 | LTA4H (0.67) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL1136688 | 0.97 | LTA4H (0.63) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL5943091 | 0.93 | ALDH1A1 (0.64) | LTA4HTSHRMAPTNR1H2BAX | |
| Diphenylether SCHEMBL27982791 | 0.92 | LTA4H (0.71) | LTA4HTSHRMAPTNR1H2BAX | |
| Anisole SCHEMBL29291357 | 0.89 | LTA4H (0.78) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL3843978 | 0.88 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL3842527 | 0.88 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL391385 | 0.88 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL29477934 | 0.87 | SLC6A4 (0.55) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL18096778 | 0.87 | SLC6A4 (0.55) | LTA4HTSHRMAPTNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1084 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250101021-A1 | METHODS OF MAKING TOLEBRUTINIB | PRINCIPIA BIOPHARMA INC. (US) | 2025-03-27 | — | — | US | claimed |
| CN-119384411-A | Method for preparing tolmetinib | 普林斯匹亚生物制药公司 | 2025-01-28 | — | — | CN | claimed |
| CN-119101000-A | Preparation method of 2,4, 6-tris [ (1, 1-biphenyl) -4-yl ] -1,3, 5-triazine | 重庆新征程生物医药有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-118858473-A | Polybrominated diphenyl ether detection method based on QuEChERS-EMR method combined with GC-NCI/MS/MS | 重庆市计量质量检测研究院 | 2024-10-29 | — | — | CN | claimed |
| US-20240071738-A1 | METHOD OF IMPROVING A MASS SPECTROMETER, MODULE FOR IMPROVING A MASS SPECTROMETER AND AN IMPROVED MASS SPECTROMETER | GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2024-02-29 | — | — | US | claimed |
| CN-117483744-A | Modified nano zero-valent iron and preparation method and application thereof | 华南师范大学 | 2024-02-02 | — | — | CN | claimed |
| WO-2023244587-A1 | METHODS OF MAKING TOLEBRUTINIB | GENZYME CORPORATION (US) | 2023-12-21 | — | — | WO | claimed |
| CN-116947802-A | Diaryl ether compound based on complex functional aromatic hydrocarbon and preparation method and application thereof | 华东理工大学 | 2023-10-27 | — | — | CN | claimed |
| CN-219784296-U | Decompression rectification flue gas absorption device of easy-sublimation 4-bromodiphenyl | 中钢集团鞍山热能研究院有限公司 | 2023-10-03 | — | — | CN | claimed |
| CN-114085300-B | Modified polybutadiene resin and preparation method and application thereof | 南亚新材料科技股份有限公司 | 2023-09-15 | — | — | CN | claimed |
| WO-1993004223-A1 | MICROPOROUS HOLLOW FIBER OR FILM MEMBRANE OF POLY(PHENYLENE SULFIDE) (PPS) | THE DOW CHEMICAL COMPANY (US) | 1993-03-04 | — | — | WO | claimed |
| US-5064580-A | Heating, extrusion, coagulation, leaching out of plasticizer | THE DOW CHEMICAL COMPANY (US) | 1991-11-12 | — | — | US | claimed |
| US-5043112-A | Dissolving polyphenylene sulfide in hot melted high-boiling boiling organic solvent, shaping, desolventizing, cooling | THE DOW CHEMICAL COMPANY (US) | 1991-08-27 | — | — | US | claimed |
| EP-0429688-A1 | Process for preparing articles of crystallized poly(etheretherketone)-type polymers and the articles prepared thereby | THE DOW CHEMICAL COMPANY (US) | 1991-06-05 | — | — | EP | claimed |
| EP-0255794-B1 | PROCESS FOR PREPARING AN AROMATIC ACID | RHONE-POULENC CHIMIE (FR) | 1990-11-07 | — | — | EP | claimed |
| US-4922010-A | Processes for preparing 2-substituted propionic acid and derivatives thereof | UBE INDUSTRIES, LTD. (JP) | 1990-05-01 | — | — | US | claimed |
| US-4904426-A | MOCROPOROUS; AROMATIC RING-CONTAINING SOLVENT; EXTRUSION, QUENCHING, LEACHING, DRYING | THE DOW CHEMICAL COMPANY (US) | 1990-02-27 | — | — | US | claimed |
| US-4897307-A | FILM, MEMBRANE, SHEET, FIBER | THE DOW CHEMICAL COMPANY (US) | 1990-01-30 | — | — | US | claimed |
| EP-0144178-B1 | CYANOACRYLATE ADHESIVE COMPOSITION HAVING SUSTAINED TOUGHNESS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-08-17 | — | — | EP | claimed |
| EP-0144178-A1 | Cyanoacrylate adhesive composition having sustained toughness | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1985-06-12 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250101021-A1 | METHODS OF MAKING TOLEBRUTINIB | ABL1, JAK2, JAK1 | LTA4H 3302/4885TSHR 203/4885MAPT 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.