Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.54 |
| ▸ | BAX | Q07812 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.45 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314422 | 0.97 | LTA4H (0.67) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL18105336 | 0.97 | LTA4H (0.67) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL5943091 | 0.90 | ALDH1A1 (0.64) | LTA4HTSHRMAPTNR1H2BAX | |
| Diphenylether SCHEMBL27982791 | 0.89 | LTA4H (0.71) | LTA4HTSHRMAPTNR1H2BAX | |
| Anisole SCHEMBL29291357 | 0.86 | LTA4H (0.78) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL3842527 | 0.86 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL3843978 | 0.86 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL391385 | 0.86 | MAPT (0.74) | LTA4HTSHRMAPTMAOAALDH1A1 | |
| SCHEMBL29477934 | 0.85 | SLC6A4 (0.55) | LTA4HTSHRMAPTNR1H2BAX | |
| SCHEMBL18096778 | 0.85 | SLC6A4 (0.55) | LTA4HTSHRMAPTNR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620869-B | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-113620869-A | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-118791384-A | Synthesis process of famoxadone intermediate 2- (4-phenoxyphenyl) ethyl lactate | 安徽广信农化股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-116730939-A | Preparation method of famoxadone characteristic impurities | 如东众意化工有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-113620869-B | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113620869-A | Preparation method of betrixaban | 江西同和药业股份有限公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-2019106-B1 | (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same | ROHM & HAAS (US) | 2013-11-27 | — | — | EP | disclosed |
| US-7956125-B2 | (Thio)phenoxy phenyl silane compostion and method for making same | ROHM AND HAAS COMPANY (US) | 2011-06-07 | — | — | US | disclosed |
| EP-1896434-B1 | SUBSTITUTED HETEROARYL AMIDE MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NFkB ACTIVITY AND USE THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2011-02-23 | — | — | EP | disclosed |
| US-7642262-B2 | Arylipiperdinopropanol and arylipiperazinopropanol derivatives and pharmaceuticals containing the same | ASUBIO PHARMA CO., LTD. (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20090039313-A1 | (Thio)phenoxy phenyl silane compostion and method for making same | ROHM AND HAAS COMPANY (US) | 2009-02-12 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0958280-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-11-24 | — | — | EP | disclosed |
| WO-1999023072-A1 | ARYLPIPERIDINOPROPANOL AND ARYLPIPERAZINOPROPANOL DERIVATIVES AND PHARMACEUTICALS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1999-05-14 | — | — | WO | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |
| EP-0024943-B1 | 5,6,7-TRINOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | TORAY INDUSTRIES, INC. (JP) | 1983-08-17 | — | — | EP | disclosed |
| US-4301164-A | FOR USE AS ANTIULCER AGENTS, HYPOTENSIVE AGENTS, ANTITHROMBOSIC AGENTS | TORAY INDUSTRIES, INC. (JP) | 1981-11-17 | — | — | US | disclosed |
| EP-0024943-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI2 derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1981-03-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090039313-A1 | (Thio)phenoxy phenyl silane compostion and method for making same | TPMT, TTR, TST | LTA4H 671/4885TSHR 3707/4885MAPT 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.