SCHEMBL29377571

SCHEMBL29377571

CCc1cc(/C=C2\SC(=S)N(CC(=O)O)C2=O)ccc1O

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ PTPN12 Q05209 1/20 0.64
▸ PTPN22 Q9Y2R2 1/20 0.64
▸ AKR1B1 P15121 8/20 0.62
▸ KMT2A Q03164 1/20 0.60
▸ MMP3 P08254 3/20 0.59
▸ PTPN1 P18031 3/20 0.59
▸ MMP13 P45452 3/20 0.59
▸ FABP4 P15090 1/20 0.59
▸ PDE4B Q07343 1/20 0.58
▸ GFER P55789 1/20 0.58
▸ ADAMTS5 Q9UNA0 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20558691 1.00 PTPN12 (0.64) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL20558693 1.00 PTPN12 (0.64) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL3764675 0.88 KMT2A (0.71) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL3764677 0.88 KMT2A (0.71) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL20558643 0.87 PTPN12 (0.65) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL20558641 0.87 PTPN12 (0.65) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL6884614 0.85 PTPN22 (0.69) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL6884607 0.85 PTPN22 (0.69) PTPN12PTPN22AKR1B1KMT2AMMP3
SCHEMBL20558689 0.85 FABP4 (0.81) AKR1B1KMT2APTPN1FABP4PDE4B
SCHEMBL20558690 0.85 FABP4 (0.81) AKR1B1KMT2APTPN1FABP4PDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584590-A1 PROXIMITY INDUCING SYSTEM AND USES THEREOF SORBONNE UNIVERSITE (FR) 2025-07-16 — — EP disclosed
WO-2024052353-A1 PROXIMITY INDUCING SYSTEM AND USES THEREOF SORBONNE UNIVERSITE (FR) 2024-03-14 — — WO disclosed
EP-3947355-A1 SPLIT PHOTOACTIVE YELLOW PROTEIN COMPLEMENTATION SYSTEM AND USES THEREOF Paris Sciences et Lettres (FR) 2022-02-09 — — EP disclosed
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