Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.71 |
| ▸ | CES2 | O00748 | 9/20 | 0.53 |
| ▸ | CES1 | P23141 | 4/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octane SCHEMBL5026156 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TDP1CES2CES1PPARG | |
| Heptane SCHEMBL1420888 | 0.97 | ALDH1A1 (0.67) | ALDH1A1TDP1CES2CES1PPARG | |
| Hexane SCHEMBL28612680 | 0.94 | ALDH1A1 (0.62) | ALDH1A1TDP1CES2CES1AKR1B1 | |
| Butanone SCHEMBL20299575 | 0.93 | ALDH1A1 (0.71) | ALDH1A1TDP1CES2CES1AKR1B1 | |
| Hexane SCHEMBL8397988 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TDP1CES2CES1GPR84 | |
| Butanone SCHEMBL11031490 | 0.88 | CES2 (0.57) | ALDH1A1TDP1CES2CES1AKR1B1 | |
| 1-Pentanol SCHEMBL3227511 | 0.88 | SMN1; SMN2 (0.67) | ALDH1A1TDP1CES2CES1AKR1B1 | |
| Butanone SCHEMBL11812300 | 0.87 | ALDH1A1 (0.62) | ALDH1A1TDP1CES2CES1AKR1B1 | |
| Butanone SCHEMBL29197456 | 0.86 | CES2 (0.59) | ALDH1A1TDP1CES2CES1PPARG | |
| 1-Hexanol SCHEMBL11256968 | 0.86 | ALDH1A1 (0.68) | ALDH1A1TDP1CES2CES1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11958798-B2 | Process for the preparation of iloprost | EUROAPI HUNGARY LIMITED LIABILITY COMPANY (HU) | 2024-04-16 | — | — | US | disclosed |
| EP-4192839-A1 | REMDESIVIR INTERMEDIATES | Richter Gedeon Nyrt. (HU) | 2023-06-14 | — | — | EP | disclosed |
| US-20230115500-A1 | PROCESS FOR THE PREPARATION OF ILOPROST | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2023-04-13 | — | — | US | disclosed |
| US-11535580-B2 | Process for the preparation of iloprost | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2022-12-27 | — | — | US | disclosed |
| CN-113233948-B | Method for separating hexane-ethanol-butanone system by two-tower pressure-swing batch rectification | 青岛科技大学 | 2022-04-08 | — | — | CN | disclosed |
| WO-2021220196-A1 | ADHESIVE COMPOSITION, ADHESIVE FILM, PREPARATION METHOD THEREOF AND ADHESIVE TAPE COMPRISING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-11-04 | — | — | WO | disclosed |
| CN-113233948-A | Method for separating hexane-ethanol-butanone system by two-tower pressure-swing batch rectification | 青岛科技大学 | 2021-08-10 | — | — | CN | disclosed |
| US-20210147329-A1 | PROCESS FOR THE PREPARATION OF ILOPROST | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. (HU) | 2021-05-20 | — | — | US | disclosed |
| CN-112513111-A | Adhesive composition, adhesive film, laminate and method for producing the same | 3M创新有限公司 | 2021-03-16 | — | — | CN | disclosed |
| WO-2021019359-A1 | ADHESIVE COMPOSITION, ADHESIVE FILM, LAMINATE AND PREPARATION METHOD THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-02-04 | — | — | WO | disclosed |
| US-4917826-A | TREATING DIABETES AND OBESITY | THE UPJOHN COMPANY (US) | 1990-04-17 | — | — | US | disclosed |
| US-4867915-A | LIPOXYGENASE INHIBITORS, ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-09-19 | — | — | US | disclosed |
| US-4743683-A | FOR DYE BLEACH PROCESS, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1988-05-10 | — | — | US | disclosed |
| US-4661437-A | COLORFASTNESS | CIBA-GEIGY AG (CH) | 1987-04-28 | — | — | US | disclosed |
| US-4521598-A | 3-Azidocephalosporins | ELI LILLY AND COMPANY (US) | 1985-06-04 | — | — | US | disclosed |
| US-4510142-A | ANTIINFLAMMATORY OR ANALGESIC AGNET | PIERRE FABRE S.A. (FR) | 1985-04-09 | — | — | US | disclosed |
| EP-0136177-A2 | 3-Azidocephalosporins as intermediates and novel antibacterial agents | ELI LILLY AND COMPANY (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4343647-A | Substituted benzyltrialkylammonium salts and their use as plant growth regulatory control agents | THE DOW CHEMICAL COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4172854-A | MAGNESIUM CHROMITE | PETRO-TEX CHEMICAL CORPORATION (US) | 1979-10-30 | — | — | US | disclosed |
| US-4055672-A | Controlled atmosphere package | STANDARD PACKAGING CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147329-A1 | PROCESS FOR THE PREPARATION OF ILOPROST | PTGIS, PTGER1, PTGIR | ALDH1A1 1368/4885TDP1 4712/4885CES2 4392/4885 |
| US-20230115500-A1 | PROCESS FOR THE PREPARATION OF ILOPROST | PTGIS, PTGER1, PTGIR | ALDH1A1 1368/4885TDP1 4712/4885CES2 4392/4885 |
| US-11535580-B2 | Process for the preparation of iloprost | PTGIS, PTGER1, PTGIR | ALDH1A1 1368/4885TDP1 4712/4885CES2 4392/4885 |
| US-11958798-B2 | Process for the preparation of iloprost | PTGIS, PTGER1, PTGIR | ALDH1A1 1368/4885TDP1 4712/4885CES2 4392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.