SCHEMBL29378147

SCHEMBL29378147

C/C=C\C#C[C@]1(C(F)(F)F)NC(=O)Nc2ccc(Cl)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 2/20 0.41
CYP46A1 Q9Y6A2 4/20 0.40
AKR1B1 P15121 4/20 0.39
NR1I2 O75469 1/20 0.39
NR3C1 P04150 1/20 0.39
PGR P06401 1/20 0.39
ADRB1 P08588 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
MAPT P10636 1/20 0.39
CNR1 P21554 1/20 0.39
SLC6A2 P23975 1/20 0.39
HTR2A P28223 1/20 0.39
HTR2C P28335 1/20 0.39
MAPK1 P28482 1/20 0.39
AGTR1 P30556 1/20 0.39
CCKBR P32239 1/20 0.39
PPARG P37231 1/20 0.39
OPRK1 P41145 1/20 0.39
SLC6A3 Q01959 1/20 0.39
PDE4D Q08499 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1045118 0.80 CYP46A1 (0.61) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL1152579 0.80 CYP46A1 (0.61) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL29399335 0.80 CYP46A1 (0.61) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL6905458 0.80 PDE7A (0.48) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL6905795 0.66 PDE7A (0.48) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL6905802 0.66 PDE7A (0.48) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL6905798 0.66 PDE7A (0.48) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL29393057 0.64 PDE7A (0.45) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL4088810 0.64 PDE7A (0.45) PDE7ACYP46A1AKR1B1NR1I2NR3C1
SCHEMBL1046528 0.64 PDE7A (0.45) PDE7ACYP46A1AKR1B1NR1I2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637693-B2 Anellosomes and methods of use FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2026-05-26 US disclosed
US-20260098280-A1 SURFACE-MODIFIED VIRAL PARTICLES AND MODULAR VIRAL PARTICLES FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2026-04-09 US disclosed
US-12540337-B2 Surface-modified viral particles and modular viral particles FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2026-02-03 US disclosed
US-20260009050-A1 ANELLOSOMES FOR DELIVERING SECRETED THERAPEUTIC MODALITIES FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2026-01-08 US disclosed
US-20250320465-A1 COMPOSITIONS COMPRISING MODIFIED ANELLOVIRUS CAPSID PROTEINS AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2025-10-16 US disclosed
US-20250257368-A1 IN VITRO ASSEMBLY OF ANELLOVIRUS CAPSIDS ENCLOSING RNA FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2025-08-14 US disclosed
US-20250171807-A1 SURFACE-MODIFIED VIRAL PARTICLES AND MODULAR VIRAL PARTICLES FLAGSHIP PIONEERING INNOVATIONS V, INC. 2025-05-29 US disclosed
WO-2025080985-A1 TISSUE SPECIFIC ANELLOVECTOR DELIVERY FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2025-04-17 WO disclosed
EP-4526326-A2 COMPOSITIONS COMPRISING MODIFIED ANELLOVIRUS CAPSID PROTEINS AND USES THEREOF Flagship Pioneering Innovations V, Inc. (US) 2025-03-26 EP disclosed
US-20250059559-A1 SURFACE-MODIFIED VIRAL PARTICLES AND MODULAR VIRAL PARTICLES FLAGSHIP PIONEERING INNOVATIONS V, INC. 2025-02-20 US disclosed
CN-115867678-A Methods for identifying and characterizing dactyloviruses and uses thereof 旗舰先锋创新V股份有限公司 2023-03-28 CN disclosed
US-20230048858-A1 ANELLOSOMES FOR DELIVERING SECRETED THERAPEUTIC MODALITIES FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2023-02-16 US disclosed
US-20220372519-A1 IN VITRO ASSEMBLY OF ANELLOVIRUS CAPSIDS ENCLOSING RNA FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2022-11-24 US disclosed
WO-2022241013-A1 ANELLOVECTORS AND METHODS OF USE FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-11-17 WO disclosed
WO-2022170195-A1 HYBRID AAV-ANELLOVECTORS FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-08-11 WO disclosed
WO-2022140560-A1 IN VITRO ASSEMBLY OF ANELLOVIRUS CAPSIDS ENCLOSING RNA FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) 2022-06-30 WO disclosed
EP-3433380-B1 DRUGS, PHARMACOGENOMICS AND BIOMARKERS FOR ACTIVE LONGEVITY UNIV INDIANA RES & TECH CORP (US) 2022-06-08 EP disclosed
US-20220073950-A1 ANELLOSOMES FOR DELIVERING PROTEIN REPLACEMENT THERAPEUTIC MODALITIES FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2022-03-10 US disclosed
US-20220042042-A1 ANELLOSOMES AND METHODS OF USE FLAGSHIP PIONEERING, INC. 2022-02-10 US disclosed
US-20220040117-A1 ANELLOSOMES FOR DELIVERING INTRACELLULAR THERAPEUTIC MODALITIES FLAGSHIP PIONEERING INNOVATIONS V INC (US) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637693-B2 Anellosomes and methods of use TAP2, UPF1, TAP1 PDE7A 3304/4885CYP46A1 4558/4885AKR1B1 3774/4885
US-20260009050-A1 ANELLOSOMES FOR DELIVERING SECRETED THERAPEUTIC MODALITIES UPF1, EXOSC4, STING1 PDE7A 4211/4885CYP46A1 4417/4885AKR1B1 3310/4885
US-12540337-B2 Surface-modified viral particles and modular viral particles APOL1, SAAL1, UFL1 PDE7A 3896/4885CYP46A1 4630/4885AKR1B1 3754/4885
US-20260098280-A1 SURFACE-MODIFIED VIRAL PARTICLES AND MODULAR VIRAL PARTICLES SAAL1, APOL1, UFL1 PDE7A 4234/4885CYP46A1 4662/4885AKR1B1 3959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.