Sulfuric Acid

Sulfuric Acid

SCHEMBL29378161

O=S(=O)(O)O.Oc1ccc2ccccc2n1

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.47
AR P10275 1/20 0.44
NCF1 P14598 2/20 0.43
CYP1A2 P05177 2/20 0.43
NOS2 P35228 1/20 0.43
BACE1 P56817 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 4/20 0.43
PRNP P04156 2/20 0.43
RXFP1 Q9HBX9 2/20 0.43
CNR2 P34972 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
MAPK10 P53779 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 2/20 0.41
RAB9A P51151 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL434092 1.00 MGAM (0.47) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL31183024 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL27909567 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412226 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412224 0.90 MGAM (0.43) MGAMARNCF1CYP1A2NOS2
Fluoride SCHEMBL28218526 0.90 NCF1 (0.46) MGAMARNCF1CYP1A2NOS2
SCHEMBL84064 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
SCHEMBL6140328 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
SCHEMBL29376435 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412225 0.88 MGAM (0.44) MGAMARNCF1CYP1A2NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114010511-A Hair dye, color developing agent and using method of double-agent oxidation type hair dye 章华化妆品科技有限公司 2022-02-08 CN disclosed