Sulfuric Acid

Sulfuric Acid

SCHEMBL434092

O=S(=O)(O)O.Oc1ccc2ccccc2n1

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.47
AR P10275 1/20 0.44
NCF1 P14598 2/20 0.43
CYP1A2 P05177 2/20 0.43
NOS2 P35228 1/20 0.43
BACE1 P56817 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
KDM4E B2RXH2 4/20 0.43
PRNP P04156 2/20 0.43
RXFP1 Q9HBX9 2/20 0.43
CNR2 P34972 1/20 0.43
HDAC8 Q9BY41 1/20 0.43
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
MAPK10 P53779 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
LMNA P02545 2/20 0.41
RAB9A P51151 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL29378161 1.00 MGAM (0.47) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL31183024 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL27909567 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412226 0.98 MGAM (0.46) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412224 0.90 MGAM (0.43) MGAMARNCF1CYP1A2NOS2
Fluoride SCHEMBL28218526 0.90 NCF1 (0.46) MGAMARNCF1CYP1A2NOS2
SCHEMBL84064 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
SCHEMBL6140328 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
SCHEMBL29376435 0.89 NCF1 (0.52) MGAMARNCF1CYP1A2NOS2
Sulfuric Acid SCHEMBL412225 0.88 MGAM (0.44) MGAMARNCF1CYP1A2NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1042 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
CN-116570533-A Quick coloring hair dye and preparation method thereof 章华化妆品科技有限公司 2023-08-11 CN claimed
EP-3113843-B1 COMPOSITION AND METHOD FOR ENHANCING WOUND HEALING TUFFLEY MARK (AU) 2022-12-14 EP claimed
EP-3937640-A1 A METHOD OF CONTROLLING CITRUS GREENING DISEASE UPL Limited (IN) 2022-01-19 EP claimed
CN-113599287-A Two-agent type clear water hair dyeing composition and hair dyeing method thereof 广州御采堂化妆品有限公司 2021-11-05 CN claimed
CN-111840225-A Eye drop for treating glaucoma and preparation method thereof 王信 2020-10-30 CN claimed
WO-2020183288-A1 A METHOD OF CONTROLLING CITRUS GREENING DISEASE UPL LIMITED (IN) 2020-09-17 WO claimed
CN-110476958-A A kind of cuckoo antistaling agent for cut-flowers in bottle and its preparation method and application UNIV NANJING FORESTRY 2019-11-22 CN claimed
CN-108853012-B The eye drip aqueous solution increased for treating intraocular pressure 中山万远新药研发有限公司 2019-03-15 CN claimed
CN-108853012-A The eye drip aqueous solution increased for treating intraocular pressure 中山万远新药研发有限公司 2018-11-23 CN claimed
EP-0614667-B1 Agent for preventing adhesion of thallium 201 to container NIHON MEDIPHYSICS CO LTD (JP) 2001-10-10 EP claimed
US-20010004637-A1 STABLE MEDICINAL COMPOSITIONS CONTAINING 4,5-EPOXYMORPHINANE DERIVATIVES TORAY INDUSTRIES, INC. (JP) 2001-06-21 US claimed
WO-2001022814-A1 PACKAGE-MIX AGRICULTURAL CHEMICAL COMPOSITIONS HAVING IMPROVED STABILITY MONSANTO TECHNOLOGY LLC (US) 2001-04-05 WO claimed
WO-2001005225-A1 AQUEOUS CONCENTRATE PESTICIDAL COMPOSITIONS HAVING IMPROVED DERMAL AND OCULAR SAFETY MONSANTO TECHNOLOGY LLC (US) 2001-01-25 WO claimed
CN-1237106-A Stable medicinal compositions containing 4,5-epoxymorphinane derivatives TORAY INDUSTRIES (JP) 1999-12-01 CN claimed
EP-0948965-A1 STABLE MEDICINAL COMPOSITIONS CONTAINING 4,5-EPOXYMORPHINANE DERIVATIVES TORAY INDUSTRIES, INC. (JP) 1999-10-13 EP claimed
US-5786366-A Method and apparatus for rehydrating dry skin SOBICINSKI J DANIEL (US) 1998-07-28 US claimed
US-5667762-A ADDITION OF REDUCING AGENT NIHON MEDI-PHYSICS CO., LTD. (JP) 1997-09-16 US claimed
EP-0614667-A1 Agent for preventing adhesion of thallium 201 to container NIHON MEDI-PHYSICS Co., Ltd. (JP) 1994-09-14 EP claimed
EP-0191128-A1 Topical preparations for human skin irratations TERAD International, Inc. (US) 1986-08-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010004637-A1 STABLE MEDICINAL COMPOSITIONS CONTAINING 4,5-EPOXYMORPHINANE DERIVATIVES OPRM1, OPRK1, FABP4 MGAM 756/4885AR 1048/4885NCF1 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.