Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.61 |
| ▸ | PRKACA | P17612 | 6/20 | 0.58 |
| ▸ | GSK3B | P49841 | 6/20 | 0.58 |
| ▸ | GSK3A | P49840 | 5/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.58 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.58 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.58 |
| ▸ | CLK2 | P49760 | 4/20 | 0.58 |
| ▸ | MAP4K2 | Q12851 | 4/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.58 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.58 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.58 |
| ▸ | NTRK2 | Q16620 | 3/20 | 0.58 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.58 |
| ▸ | PAK4 | O96013 | 3/20 | 0.58 |
| ▸ | CDK8 | P49336 | 2/20 | 0.58 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.58 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3226104 | 1.00 | LRRK2 (0.61) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL19533502 | 0.88 | LRRK2 (0.52) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL7060408 | 0.84 | STK3 (0.56) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL16636871 | 0.82 | LRRK2 (0.61) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL7021288 | 0.81 | LRRK2 (0.63) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL15032863 | 0.81 | JAK3 (0.68) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL2257351 | 0.80 | MAPT (0.56) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL2253936 | 0.80 | CHEK1 (0.46) | LRRK2PRKACAGSK3BGSK3ACDK5 | |
| SCHEMBL30372928 | 0.80 | LRRK2 (0.59) | LRRK2STK3CHEK1JAK3JAK2 | |
| SCHEMBL15401054 | 0.79 | LRRK2 (0.70) | LRRK2STK3STK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250276-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | MITOKININ, INC. (US) | 2025-08-07 | — | — | US | disclosed |
| CN-112585147-B | MAP4K4 inhibitors | 帝国理工学院创新有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-112236430-B | Cyclopyrazolone formamide compound and preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-02-17 | — | — | CN | disclosed |
| EP-3947390-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | Mitokinin, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| CN-114026093-A | Compositions for treating neurodegenerative and mitochondrial diseases and methods of use thereof | 麦托吉宁公司 | 2022-02-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250250276-A1 | COMPOSITIONS AND METHODS OF USING THE SAME FOR TREATMENT OF NEURODEGENERATIVE AND MITOCHONDRIAL DISEASE | PINK1, NLN, NME4 | LRRK2 171/4885PRKACA 1244/4885GSK3B 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.