Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | S100B | P04271 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397693 | 1.00 | ADRA2C (0.66) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15928733 | 1.00 | ADRA2C (0.66) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL30469317 | 1.00 | ADRA2C (0.66) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9014044 | 0.98 | ADRA2C (0.63) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4631044 | 0.98 | ADRA2C (0.63) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL533024 | 0.98 | ADRA2C (0.68) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15289763 | 0.93 | ADRA2C (0.68) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6942579 | 0.89 | ADRA2C (0.80) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7077636 | 0.86 | ADRA2C (0.77) | ADRA2CALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL22685038 | 0.86 | ALDH1A1 (0.59) | ADRA2CALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114025847-B | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |
| CN-110603273-B | Modified block copolymer, method for producing modified block copolymer, and resin composition | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-114025847-A | Compounds and compositions as modulators of TLR signaling | 神经孔疗法股份有限公司 | 2022-02-08 | — | — | CN | disclosed |