SCHEMBL533024

SCHEMBL533024

Nc1cccc(N2CCCC2)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.68
AGXT P21549 1/20 0.55
ALDH1A1 P00352 8/20 0.54
MAPT P10636 7/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
GAA P10253 4/20 0.54
KDM4E B2RXH2 3/20 0.54
ALOX15 P16050 3/20 0.54
HSD17B10 Q99714 2/20 0.54
HTT P42858 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
RECQL P46063 2/20 0.54
POLB P06746 2/20 0.54
THRB P10828 2/20 0.54
NPC1 O15118 1/20 0.54
USP2 O75604 1/20 0.54
TP53 P04637 1/20 0.54
RAB9A P51151 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29378385 0.98 ADRA2C (0.66) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL15928733 0.98 ADRA2C (0.66) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL30469317 0.98 ADRA2C (0.66) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL1397693 0.98 ADRA2C (0.66) ADRA2CAGXTALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL4631044 0.96 ADRA2C (0.63) ADRA2CAGXTALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL9014044 0.96 ADRA2C (0.63) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL15289763 0.95 ADRA2C (0.68) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL6942579 0.91 ADRA2C (0.80) ADRA2CAGXTALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL7077636 0.88 ADRA2C (0.77) ADRA2CAGXTALDH1A1MAPTMEN1
SCHEMBL2627250 0.84 ADRA2C (0.71) ADRA2CALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
WO-2022112473-A1 HAIR COLORING COMPOSITIONS WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2022-06-02 WO claimed
US-9060953-B2 1-hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions THE PROCTER & GAMBLE COMPANY (US) 2015-06-23 US claimed
US-20140289973-A1 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions WELLA OPERATIONS US, LLC 2014-10-02 US claimed
US-8784505-B2 1-hexzl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions THE PROCTER & GAMBLE COMPANY (US) 2014-07-22 US claimed
EP-2628731-B1 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions PROCTER & GAMBLE (US) 2014-04-23 EP claimed
US-20130212810-A1 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 US claimed
WO-2013122990-A1 1-HEXYL-1H-PYRAZOLE-4,5-DIAMINE HEMISULFATE, AND ITS USE IN DYEING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2013-08-22 WO claimed
EP-2628731-A1 1-Hexyl-1H-pyrazole-4,5-diamine hemisulfate, and its use in dyeing compositions The Procter and Gamble Company (US) 2013-08-21 EP claimed
EP-2190834-B1 PYRIDONEAMIDE DERIVATIVES AS FOCAL ADHESION KINASE (FAK) INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER HOFFMANN LA ROCHE (CH) 2011-03-02 EP claimed
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS SYNTA PHARMACEUTICALS CORPORATION (US) 2010-10-07 US claimed
EP-2065380-A1 Pyridoneamide derivatives as focal adhesion kinase (FAK) inhibitors and their use for the treatment of cancer F.HOFFMANN-LA ROCHE AG (CH) 2009-06-03 EP claimed
US-20060223996-A1 IL-12 modulatory compounds SYNTA PHARMACEUTICALS CORP. (US) 2006-10-05 US claimed
EP-1542982-A1 HAIR DYES COMPRISING M-PHENYLENEDIAMINE DERIVATIVES AS COUPLING COMPONENTS Henkel Kommanditgesellschaft auf Aktien (DE) 2005-06-22 EP claimed
WO-2004031164-A1 HAIR DYES COMPRISING M-PHENYLENEDIAMINE DERIVATIVES AS COUPLING COMPONENTS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2004-04-15 WO claimed
EP-4716523-A1 PROCESS FOR PRODUCING HAIR DYES Laboratoire Biosthetique Kosmetik GmbH & Co. KG (DE) 2026-04-01 EP disclosed
WO-1998017651-A1 1-PHENYL-BENZIMIDAZOLE COMPOUNDS AND THEIR USE AS BAGA-A RECEPTOR MODULATORS NEUROSEARCH A/S (DK) 1998-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223996-A1 IL-12 modulatory compounds IL2, IL4, IFNG ADRA2C 1238/4885AGXT 3004/4885ALDH1A1 1381/4885
US-20140289973-A1 1-Hexyl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions PPOX, XDH, DPYD ADRA2C 3491/4885AGXT 368/4885ALDH1A1 210/4885
US-20130212810-A1 1-Hexzl-1H-Pyrazole-4,5-Diamine Hemisulfate, and Its Use in Dyeing Compositions PPOX, XDH, TYR ADRA2C 4062/4885AGXT 207/4885ALDH1A1 283/4885
US-20100256132-A1 IL-12 MODULATORY COMPOUNDS IL2, IL4, IFNG ADRA2C 1238/4885AGXT 3004/4885ALDH1A1 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.