SCHEMBL29378658

SCHEMBL29378658

CC(C)C[C@H](NC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.69

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 5/20 0.69
KISS1R Q969F8 14/20 0.67
NMUR2 Q9GZQ4 1/20 0.62
NMUR1 Q9HB89 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29379177 0.95 KISS1R (0.67) CXCR4KISS1RNMUR2NMUR1
SCHEMBL30186660 0.90 GNRHR (0.67) CXCR4KISS1RNMUR2NMUR1
SCHEMBL31683258 0.90 CXCR4 (0.71) CXCR4KISS1R
SCHEMBL29389088 0.88 CXCR4 (0.65) CXCR4NMUR2NMUR1
Kisspeptin-10 SCHEMBL29376534 0.88 KISS1R (0.77) KISS1R
SCHEMBL30530852 0.88 KISS1R (0.77) KISS1R
Kisspeptin-10 SCHEMBL15930211 0.88 KISS1R (0.77) KISS1R
SCHEMBL29379050 0.88 KISS1R (0.77) KISS1R
Kisspeptin-10 SCHEMBL20865531 0.88 KISS1R (0.77) KISS1R
SCHEMBL17345398 0.88 KISS1R (0.77) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220040253-A1 Agonists of Human Kisspeptin Receptor for Modulating Sexual Desire Université de Liège (BE) 2022-02-10 US claimed
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) UNIV LELAND STANFORD JUNIOR (US) 2026-02-19 US disclosed
EP-3811080-B1 IN VITRO METHOD FOR THE DIAGNOSIS OF ECTOPIC PREGNANCY UNIV CORDOBA (ES) 2026-02-11 EP disclosed
EP-3650464-B1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND SHANGPHARMA INNOVATION INC (US) 2025-11-05 EP disclosed
US-20250223580-A1 PROGRAMMABLE NUCLEASE-PEPTIDASE COMPOSITIONS THE BROAD INSTITUTE, INC. 2025-07-10 US disclosed
WO-2025133225-A1 PHARMACEUTICAL COMBINATION OF PEPTIDE-GLY AND PEPTIDYLGLYCINE ALPHA-AMIDATING MONOOXYGENASE (PAM) PAM THERAGNOSTICS GMBH (DE) 2025-06-26 WO disclosed
US-12338464-B2 Clonal strains of attenuated vaccinia viruses and methods of use thereof GENELUX CORPORATION (US) 2025-06-24 US disclosed
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2025-06-05 US disclosed
EP-4545553-A2 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND ShangPharma Innovation Inc. (US) 2025-04-30 EP disclosed
US-20250051763-A1 METHODS AND SYSTEMS FOR CONDITIONALLY REGULATING GENE EXPRESSION FUNDACAO D. ANNA DE SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD FOUNDATION (PT) 2025-02-13 US disclosed
CN-116535519-A Fermentation production method of gonadotropin releasing hormone hexamer-kis peptide 安徽农业大学 2023-08-04 CN disclosed
US-20230008052-A1 CLONAL STRAINS OF ATTENUATED VACCINIA VIRUSES AND METHODS OF USE THEREOF GENELUX CORPORATION 2023-01-12 US disclosed
WO-2022253998-A1 PEPTIDES WITH MUCIN-BINDING PROPERTIES UNIVERSITY OF COPENHAGEN (DK) 2022-12-08 WO disclosed
US-20220281989-A1 GPCR BINDING PROTEINS AND SYNTHESIS THEREOF Twist Bioscience Corporation 2022-09-08 US disclosed
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound XDCEXPLORER (SHANGHAI) CO., LTD. (CN) 2022-08-30 US disclosed
US-11407837-B2 GPCR binding proteins and synthesis thereof Twist Bioscience Corporation (US) 2022-08-09 US disclosed
US-20220242908-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2022-08-04 US disclosed
US-20220213142-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2022-07-07 US disclosed
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS ON TARGET THERAPEUTICS LLC 2022-05-05 US disclosed
US-20220040253-A1 Agonists of Human Kisspeptin Receptor for Modulating Sexual Desire Université de Liège (BE) 2022-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135633-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG CXCR4 432/4885KISS1R 2641/4885NMUR2 2031/4885
US-11427615-B2 Peptide compound and application thereof, and composition containing peptide compound KISS1R, VIP, NPY1R CXCR4 1122/4885KISS1R 1/4885NMUR2 1452/4885
US-20220213142-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, VIP, SSTR3 CXCR4 563/4885KISS1R 1/4885NMUR2 441/4885
US-20260049331-A1 Sense-and-Response of Proteins, Peptides, and Small Molecules Using Ligand-Induced Dimerization Activating RNA Editing (LIDAR) ADAR, ZFR, SLIRP CXCR4 1780/4885KISS1R 1227/4885NMUR2 1950/4885
US-20220242908-A1 PEPTIDE COMPOUND AND APPLICATION THEREOF, AND COMPOSITION CONTAINING PEPTIDE COMPOUND KISS1R, NPY1R, GLP1R CXCR4 1598/4885KISS1R 1/4885NMUR2 1982/4885
US-20250179130-A1 METHODS AND SYSTEMS FOR DESIGNING AND/OR CHARACTERIZING SOLUBLE LIPIDATED LIGAND AGENTS LDLR, HDLBP, LIPG CXCR4 432/4885KISS1R 2641/4885NMUR2 2031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.