SCHEMBL29379306

SCHEMBL29379306

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](N)CCCCN)C(C)C)C(C)C)[C@@H](C)CC)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

nearest known ligand 0.78

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 4/20 0.78
▸ CRHR1 P34998 1/20 0.73
▸ CRHR2 Q13324 1/20 0.73
▸ CALCR P30988 4/20 0.69
▸ HCRTR1 O43613 1/20 0.67
▸ HCRTR2 O43614 1/20 0.67
▸ NMBR P28336 1/20 0.65
▸ GRPR P30550 1/20 0.65
▸ OPRD1 P41143 2/20 0.64
▸ C5AR1 P21730 1/20 0.63
▸ CCKBR P32239 1/20 0.63
▸ GLP1R P43220 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351932 0.91 CRHR1 (0.74) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL30432393 0.90 F2 (0.72) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL30498570 0.89 CALCR (0.80) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL30495663 0.89 F2 (0.71) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL30712965 0.89 CALCR (0.71) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL31362091 0.88 CRHR1 (0.69) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL30576931 0.88 F2 (0.73) F2CRHR1CRHR2CALCRHCRTR1
SCHEMBL31182519 0.88 CALCR (0.68) F2CALCRC5AR1
SCHEMBL29377468 0.88 CALCR (0.73) CRHR1CRHR2CALCRGLP1R
SCHEMBL29939733 0.87 CALCR (0.73) F2CRHR1CRHR2CALCRHCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119432862-A Preparation and application of dsRNA of plutella xylostella neuropeptide F genes NPF1 and NPF2 江苏省农业科学院 2025-02-14 — — CN claimed
WO-2024133655-A1 PEST CONTROL COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-06-27 — — WO claimed
US-11364285-B2 Methods, compositions, and molecular targets that exploit synergies and symbioses in the termite gut PURDUE RESEARCH FOUNDATION (US) 2022-06-21 — — US claimed
EP-3621632-B1 ANTIMICROBIAL PEPTIDES WITH ALPHA-CORE HELICES LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) 2025-08-13 — — EP disclosed
CN-119432862-A Preparation and application of dsRNA of plutella xylostella neuropeptide F genes NPF1 and NPF2 江苏省农业科学院 2025-02-14 — — CN disclosed
CN-119432862-A Preparation and application of dsRNA of plutella xylostella neuropeptide F genes NPF1 and NPF2 江苏省农业科学院 2025-02-14 — — CN disclosed
CN-119432862-A Preparation and application of dsRNA of plutella xylostella neuropeptide F genes NPF1 and NPF2 江苏省农业科学院 2025-02-14 — — CN disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 — — US disclosed
CN-118127021-B DsRNA based on neuropeptide NPF gene, and preparation method and application thereof 青岛农业大学 2024-07-26 — — CN disclosed
WO-2024133655-A1 PEST CONTROL COMPOSITION Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2024-06-27 — — WO disclosed
CN-118127021-A DsRNA based on neuropeptide NPF gene, and preparation method and application thereof 青岛农业大学 2024-06-04 — — CN disclosed
US-20220380430-A1 Non-Transgenic Functional Rescue of Neuropeptides WORCESTER POLYTECHNIC INSTITUTE 2022-12-01 — — US disclosed
WO-2022246187-A1 NON-TRANSGENIC FUNCTIONAL RESCUE OF NEUROPEPTIDES ORCESTER POLYTECHNIC INSTITUTE (US) 2022-11-24 — — WO disclosed
US-20220281989-A1 GPCR BINDING PROTEINS AND SYNTHESIS THEREOF Twist Bioscience Corporation 2022-09-08 — — US disclosed
US-11407837-B2 GPCR binding proteins and synthesis thereof Twist Bioscience Corporation (US) 2022-08-09 — — US disclosed
US-11364285-B2 Methods, compositions, and molecular targets that exploit synergies and symbioses in the termite gut PURDUE RESEARCH FOUNDATION (US) 2022-06-21 — — US disclosed
US-20220040253-A1 Agonists of Human Kisspeptin Receptor for Modulating Sexual Desire Université de Liège (BE) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR F2 3164/4885CRHR1 195/4885CRHR2 386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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