SCHEMBL31362091

CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)[C@@H](C)O)C(C)C

nearest known ligand 0.69

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	CRHR1	P34998	1/20	0.69

▸	CRHR2	Q13324	1/20	0.69

▸	CALCR	P30988	4/20	0.67

▸	HCRTR1	O43613	1/20	0.66

▸	HCRTR2	O43614	1/20	0.66

▸	F2	P00734	4/20	0.66

▸	NPY2R	P49146	7/20	0.64

▸	NPY4R	P50391	7/20	0.64

▸	NPY5R	Q15761	7/20	0.64

▸	NPY1R	P25929	5/20	0.64

▸	NMBR	P28336	1/20	0.63

▸	GRPR	P30550	1/20	0.63

▸	CCKBR	P32239	2/20	0.61

▸	GLP1R	P43220	2/20	0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29351932	0.97	CRHR1 (0.74)	CRHR1CRHR2CALCRHCRTR1HCRTR2
SCHEMBL29496391	0.94	NPY2R (0.72)	CALCRNPY2RNPY4RNPY5RNPY1R
Neuropeptide Y(Npy) SCHEMBL29557110	0.94	HCRTR1 (0.73)	CRHR1CRHR2CALCRHCRTR1HCRTR2
SCHEMBL29440046	0.91	CRHR1 (0.77)	CRHR1CRHR2CALCRHCRTR1HCRTR2
SCHEMBL29496288	0.91	NPY2R (0.74)	CRHR1CRHR2CALCRNPY2RNPY4R
SCHEMBL29397746	0.91	NPY2R (0.73)	CALCRNPY2RNPY4RNPY5RNPY1R
SCHEMBL29526997	0.90	NPY2R (0.72)	CALCRHCRTR1HCRTR2NPY2RNPY4R
SCHEMBL13248707	0.89	NPY2R (0.80)	CALCRNPY2RNPY4RNPY5RNPY1R
Neuropeptide-Y SCHEMBL31042464	0.89	NPY2R (0.73)	CRHR1CRHR2CALCRHCRTR1HCRTR2
SCHEMBL29379306	0.88	F2 (0.78)	CRHR1CRHR2CALCRHCRTR1HCRTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3307768-B1	SELECTIVE PYY COMPOUNDS AND USES THEREOF	NOVO NORDISK AS (DK)	2025-01-29	—	—	EP	disclosed