SCHEMBL29519602

SCHEMBL29519602

Nc1ncnc2c1ncn2C1C[C@H](O)[C@@H](COP(=O)(O)O[C@H]2C[C@H](n3cnc4c(N)ncnc43)O[C@@H]2CO)O1

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.69
ENPP1 P22413 3/20 0.65
P2RY1 P47900 3/20 0.65
RNASEL Q05823 2/20 0.56
DTYMK P23919 2/20 0.56
ADORA1 P30542 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24864688 1.00 POLB (0.69) POLBENPP1P2RY1RNASELDTYMK
SCHEMBL31454757 0.94 POLB (0.70) POLBENPP1P2RY1RNASELADORA1
SCHEMBL29382612 0.94 POLB (0.70) POLBENPP1P2RY1RNASELADORA1
SCHEMBL17269644 0.93 POLB (0.60) POLBENPP1P2RY1RNASELDTYMK
SCHEMBL17268345 0.93 POLB (0.60) POLBENPP1P2RY1RNASELDTYMK
SCHEMBL10034040 0.92 POLB (0.72) POLBENPP1P2RY1RNASELDTYMK
SCHEMBL10034046 0.91 POLB (0.66) POLBENPP1P2RY1DTYMKADORA1
SCHEMBL29677728 0.91 POLB (0.63) POLBENPP1P2RY1DTYMK
SCHEMBL29868797 0.91 POLB (0.63) POLBENPP1P2RY1DTYMK
SCHEMBL21447399 0.91 POLB (0.56) POLBENPP1P2RY1RNASELADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118620223-A Metal organic framework Cu-MOF fluorescent probe and application thereof in rapid detection of erythromycin in water 浙江工业大学 2024-09-10 CN claimed
EP-3718551-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENOSIS INC (US) 2026-02-04 EP disclosed
EP-3812761-B1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENOSIS INC (US) 2025-12-24 EP disclosed
EP-4053179-B1 CROSSLINKED POLY(ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS RENOSIS INC (US) 2025-08-27 EP disclosed
US-20250011276-A1 PROCESS FOR THE PREPARATION OF 1,3-BIS(ALLYLAMINO)PROPANE RENIBUS THERAPEUTICS, INC. 2025-01-09 US disclosed
US-20240384261-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2024-11-21 US disclosed
CN-118755098-A Method for rapidly detecting dichromate ions in water based on Zr-MOF fluorescent probe 浙江工业大学 2024-10-11 CN disclosed
CN-118620223-A Metal organic framework Cu-MOF fluorescent probe and application thereof in rapid detection of erythromycin in water 浙江工业大学 2024-09-10 CN disclosed
CN-118620223-A Metal organic framework Cu-MOF fluorescent probe and application thereof in rapid detection of erythromycin in water 浙江工业大学 2024-09-10 CN disclosed
US-20240254267-A1 CROSSLINKED POLY (ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS RENIBUS THERAPEUTICS, INC. 2024-08-01 US disclosed
US-20230405043-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2023-12-21 US disclosed
US-11738041-B2 Proton-binding polymers for oral administration RENOSIS, INC. (US) 2023-08-29 US disclosed
US-20230201235-A1 INHIBITION OF NIDOVIRUSES THAT ENCODE NSP15 THE UNIVERSITY OF CHICAGO (US) 2023-06-29 US disclosed
CN-116211887-A Composition for treating acid-base imbalance 特里赛达公司 2023-06-06 CN disclosed
WO-2022263807-A1 METHODS, COMPOSITIONS, AND KITS FOR PREPARING SEQUENCING LIBRARY GENEFIRST LIMITED (GB) 2022-12-22 WO disclosed
US-20220339186-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2022-10-27 US disclosed
WO-2022186813-A1 CROSSLINKED POLY(ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS TRICIDA, INC. (US) 2022-09-09 WO disclosed
EP-4053179-A1 CROSSLINKED POLY(ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS Tricida Inc. (US) 2022-09-07 EP disclosed
US-11311571-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2022-04-26 US disclosed
US-20220096534-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2022-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220339186-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 POLB 1439/4885ENPP1 1202/4885P2RY1 1026/4885
US-20230201235-A1 INHIBITION OF NIDOVIRUSES THAT ENCODE NSP15 TYMP, TYMS, ISG15 POLB 77/4885ENPP1 344/4885P2RY1 2110/4885
US-20250011276-A1 PROCESS FOR THE PREPARATION OF 1,3-BIS(ALLYLAMINO)PROPANE PBRM1, APEX1, AP1M1 POLB 101/4885ENPP1 1347/4885P2RY1 2634/4885
US-11738041-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 POLB 1439/4885ENPP1 1202/4885P2RY1 1026/4885
US-20240254267-A1 CROSSLINKED POLY (ALLYLAMINE) POLYMER PHARMACEUTICAL COMPOSITIONS PARG, PARN, AAAS POLB 1871/4885ENPP1 991/4885P2RY1 2130/4885
US-20230405043-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 POLB 1439/4885ENPP1 1202/4885P2RY1 1026/4885
US-11311571-B2 Proton-binding polymers for oral administration SLC9A1, HRH2, SLC9A2 POLB 1439/4885ENPP1 1202/4885P2RY1 1026/4885
US-20220096534-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 POLB 1439/4885ENPP1 1202/4885P2RY1 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.