SCHEMBL2938534

SCHEMBL2938534

COCC1CCCN1c1ccc(C)c(O)c1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.43
CRHR1 P34998 1/20 0.43
PPARG P37231 1/20 0.42
FPR1 P21462 3/20 0.41
FPR2 P25090 3/20 0.41
ADORA2A P29274 4/20 0.40
ADORA1 P30542 4/20 0.40
IDH1 O75874 2/20 0.40
SYK P43405 1/20 0.40
CYP1A2 P05177 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
ADORA2B P29275 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2932236 0.85 FPR1 (0.45) FFAR1CRHR1PPARGFPR1FPR2
SCHEMBL2938886 0.85 CHRNB4 (0.46) FFAR1CRHR1FPR1FPR2IDH1
SCHEMBL2937107 0.85 FPR1 (0.43) FFAR1CRHR1FPR1FPR2IDH1
SCHEMBL2941404 0.85 FFAR1 (0.43) FFAR1PPARG
SCHEMBL2935646 0.84 FPR1 (0.42) FFAR1CRHR1FPR1FPR2ADORA2A
SCHEMBL2941733 0.82 FFAR1 (0.42) FFAR1PPARG
SCHEMBL2941894 0.82 FPR1 (0.44) FFAR1FPR1FPR2ADORA2AIDH1
SCHEMBL2938017 0.82 FPR1 (0.39) FFAR1CRHR1FPR1FPR2ADORA2A
SCHEMBL13638851 0.81 ADORA2A (0.45) FFAR1CRHR1PPARGFPR1FPR2
SCHEMBL13122822 0.81 FPR1 (0.43) CRHR1FPR1FPR2ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491244-B2 Oxidizing hair coloring agents containing m-aminophenol derivatives THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US claimed
WO-2007020565-A1 OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-02-22 WO claimed
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene PROCTER & GAMBLE COMPANY, THE 2007-02-15 US claimed
EP-1752192-A1 Oxidizing hair coloring agents containing m-Aminophenol derivatives Wella Aktiengesellschaft (DE) 2007-02-14 EP claimed
EP-1752192-B1 Oxidizing hair coloring agents containing m-Aminophenol derivatives PROCTER & GAMBLE (US) 2010-02-03 EP disclosed
US-7491244-B2 Oxidizing hair coloring agents containing m-aminophenol derivatives THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US disclosed
WO-2007020565-A1 OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-02-22 WO disclosed
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene PROCTER & GAMBLE COMPANY, THE 2007-02-15 US disclosed
EP-1752192-A1 Oxidizing hair coloring agents containing m-Aminophenol derivatives Wella Aktiengesellschaft (DE) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene TACR1, KRT18, AKR1C4 FFAR1 2216/4885CRHR1 106/4885PPARG 1696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.