SCHEMBL2935646

SCHEMBL2935646

CCc1ccc(N2CCCC2COC)cc1O

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 3/20 0.42
FPR2 P25090 3/20 0.42
FFAR1 O14842 4/20 0.42
SYK P43405 1/20 0.41
IDH1 O75874 2/20 0.41
CRHR1 P34998 1/20 0.40
DRD2 P14416 1/20 0.39
F10 P00742 1/20 0.39
ADORA2A P29274 6/20 0.38
ADORA1 P30542 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2938017 0.88 FPR1 (0.39) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2937107 0.86 FPR1 (0.43) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2934509 0.85 FFAR1 (0.39) FFAR1DRD2
SCHEMBL2938534 0.84 FFAR1 (0.43) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2938886 0.83 CHRNB4 (0.46) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2932236 0.83 FPR1 (0.45) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2942012 0.83 FFAR1 (0.38) FFAR1
SCHEMBL2941894 0.80 FPR1 (0.44) FPR1FPR2FFAR1SYKIDH1
SCHEMBL2942154 0.80 FFAR1 (0.33) FFAR1DRD2
SCHEMBL2938360 0.76 CRHR1 (0.39) FPR1FPR2FFAR1SYKCRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7491244-B2 Oxidizing hair coloring agents containing m-aminophenol derivatives THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US claimed
WO-2007020565-A1 OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-02-22 WO claimed
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene PROCTER & GAMBLE COMPANY, THE 2007-02-15 US claimed
EP-1752192-A1 Oxidizing hair coloring agents containing m-Aminophenol derivatives Wella Aktiengesellschaft (DE) 2007-02-14 EP claimed
EP-1752192-B1 Oxidizing hair coloring agents containing m-Aminophenol derivatives PROCTER & GAMBLE (US) 2010-02-03 EP disclosed
US-7491244-B2 Oxidizing hair coloring agents containing m-aminophenol derivatives THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US disclosed
WO-2007020565-A1 OXIDIZING HAIR COLORING AGENTS CONTAINING M-AMINOPHENOL DERIVATIVES THE PROCTER & GAMBLE COMPANY (US) 2007-02-22 WO disclosed
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene PROCTER & GAMBLE COMPANY, THE 2007-02-15 US disclosed
EP-1752192-A1 Oxidizing hair coloring agents containing m-Aminophenol derivatives Wella Aktiengesellschaft (DE) 2007-02-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070033745-A1 Developer substance-coupler substance of 3-(1-pyrrolidinyl)phenol and 1,4-diaminobenzene TACR1, KRT18, AKR1C4 FPR1 1066/4885FPR2 1163/4885FFAR1 2216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.