Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947269 | 0.73 | TP53 (0.36) | TP53MAPTALOX15HSD17B10ADORA2B | |
| SCHEMBL27664807 | 0.72 | CA12 (0.33) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL13947265 | 0.71 | TP53 (0.35) | TP53MAPTALOX15HSD17B10ADORA2B | |
| SCHEMBL3818020 | 0.71 | — | — | |
| SCHEMBL27771574 | 0.69 | TP53 (0.31) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL5751644 | 0.69 | NFKB1 (0.31) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL3354761 | 0.69 | TP53 (0.33) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL15359079 | 0.69 | TP53 (0.33) | TP53MAPTALOX15HSD17B10NFKB1 | |
| SCHEMBL30910181 | 0.68 | ALDH1A1 (0.31) | TP53MAPTALOX15HSD17B10ALDH1A1 | |
| SCHEMBL29080120 | 0.67 | TP53 (0.35) | TP53MAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057739-A | Diazepinone derivatives and their use in the treatment of hepatitis b infections | 诺维拉治疗公司 | 2022-02-18 | — | — | CN | disclosed |