Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353420 | 0.72 | ADORA2B (0.33) | TP53MAPTALOX15HSD17B10 | |
| SCHEMBL4294976 | 0.71 | — | — | |
| SCHEMBL3356545 | 0.70 | — | — | |
| SCHEMBL29152579 | 0.69 | TP53 (0.33) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL29386151 | 0.69 | TP53 (0.33) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL5751644 | 0.69 | NFKB1 (0.31) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL6205702 | 0.69 | TP53 (0.36) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL27771574 | 0.69 | TP53 (0.31) | TP53MAPTALOX15HSD17B10CA12 | |
| SCHEMBL27602721 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL16166477 | 0.67 | TP53 (0.32) | TP53MAPTALOX15HSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681811-B | Azolidinone-vinyl fused-benzene derivatives | APPLIED RESEARCH SYSTEMS | 2010-05-26 | — | — | CN | claimed |
| CN-1681811-A | Azolidinone-vinyl fused-benzene derivatives | APPLIED RESEARCH SYSTEMS (AN) | 2005-10-12 | — | — | CN | claimed |
| CN-120077040-A | Compounds for SHP2 protein degradation and medical uses thereof | 尤比克斯治疗公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-116283916-B | Compound with Axl and c-Met kinase inhibition activity and preparation and application thereof | 中国科学院上海药物研究所 | 2024-06-11 | — | — | CN | disclosed |
| CN-118103369-A | Pyridolactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117917406-A | Heterocyclic compounds, process for their preparation and their use | 四川科伦博泰生物医药股份有限公司 | 2024-04-23 | — | — | CN | disclosed |
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-113226310-B | 15-PGDH inhibitors | 杏林制药株式会社 | 2024-03-19 | — | — | CN | disclosed |
| CN-117355522-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-112204028-B | tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-117024411-A | Isoquinoline as HPK1 inhibitor | 豪夫迈·罗氏有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-108473439-A | Pyrazolone derivative as nitroxyl donors | 卡尔迪奥克斯尔制药公司 | 2018-08-31 | — | — | CN | disclosed |
| EP-2699572-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Origenis GmbH (DE) | 2014-02-26 | — | — | EP | disclosed |
| WO-2012143143-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ORIGENIS GMBH (DE) | 2012-10-26 | — | — | WO | disclosed |
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |
| CN-1681811-B | Azolidinone-vinyl fused-benzene derivatives | APPLIED RESEARCH SYSTEMS | 2010-05-26 | — | — | CN | disclosed |
| CN-101300047-A | PI3K inhibitors for the treatment of endometriosis | SERONO LAB (CH) | 2008-11-05 | — | — | CN | disclosed |
| CN-1681811-A | Azolidinone-vinyl fused-benzene derivatives | APPLIED RESEARCH SYSTEMS (AN) | 2005-10-12 | — | — | CN | disclosed |
| CN-1335845-A | 3,4-dihydro-2H-benzo[1,4] oxazinyl-methyl [3-(1H-indol-3-yl)-alkyl]-amines | AMERICAN HOME PROD (US) | 2002-02-13 | — | — | CN | disclosed |
| CN-1304409-A | Indol-3-Yl-cyclohexyl amide derivatives for treatment of depression (5-HT1 receptor antagonists) | AMERICAN HOME PROD (US) | 2001-07-18 | — | — | CN | disclosed |