SCHEMBL2938620

SCHEMBL2938620

CCCCC1(CC)CS(=O)(=O)c2cc(OCC(=O)O)c(Br)cc2C(c2ccccc2)N1

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1362560 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL8200633 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL1362558 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL29429783 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL2843089 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL25274089 0.88 SLC10A2 (0.85) SLC10A2
SCHEMBL1361732 0.88 SLC10A2 (0.79) SLC10A2
SCHEMBL919677 0.86 SLC10A2 (0.62) SLC10A2
SCHEMBL1361642 0.85 SLC10A2 (0.74) SLC10A2
SCHEMBL2946578 0.85 SLC10A2 (0.74) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427713-B1 BENZOTHIAZEPINE DERIVATIVES FOR THE TREATMENT OF HYPERLIPIDEMIA ALBIREO AB (SE) 2010-01-06 EP disclosed
US-7125864-B2 Benzothiazepine derivatives for the treatment of hyperlipidemia ASTRAZENECA AB (SE) 2006-10-24 US disclosed
US-20050032776-A1 Benzothiazepine derivatives for the treatment of hyperlipidemia ALBIREO AB (SE) 2005-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050032776-A1 Benzothiazepine derivatives for the treatment of hyperlipidemia SLC10A2, SLC10A1, LCAT SLC10A2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.