SCHEMBL1362560

SCHEMBL1362560

CCCC[C@]1(CC)CS(=O)(=O)c2cc(OC)c(Br)cc2[C@H](c2ccccc2)N1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2843089 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL25274089 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL29429783 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL1362558 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL8200633 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL16067962 0.94 SLC10A2 (0.75) SLC10A2
SCHEMBL9961457 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452161 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452163 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452158 0.92 SLC10A2 (1.00) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067584-B2 Benzothiazepine derivatives ALBIREO AB (SE) 2011-11-29 US disclosed
US-20060094884-A1 Benzothiazepine and benzothiepine derivatives ALBIREO AB (SE) 2006-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060094884-A1 Benzothiazepine and benzothiepine derivatives SLC10A2, SLC10A1, ABCB11 SLC10A2 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.