SCHEMBL29429783

SCHEMBL29429783

CCCC[C@]1(CC)CS(=O)(=O)c2cc(OC)c(Br)cc2[C@@H](c2ccccc2)N1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC10A2 Q12908 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2843089 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL25274089 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL1362560 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL1362558 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL8200633 1.00 SLC10A2 (0.85) SLC10A2
SCHEMBL16067962 0.94 SLC10A2 (0.75) SLC10A2
SCHEMBL9961457 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452161 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452163 0.92 SLC10A2 (1.00) SLC10A2
SCHEMBL2452158 0.92 SLC10A2 (1.00) SLC10A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114096268-A Methods for increasing growth in pediatric subjects with cholestatic liver disease 米鲁姆制药公司 2022-02-25 CN disclosed
CN-114072153-A Methods for treating cholestasis 米鲁姆制药公司 2022-02-18 CN disclosed