Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 12/20 | 1.00 |
| ▸ | P2RX1 | P51575 | 10/20 | 1.00 |
| ▸ | P2RX4 | Q99571 | 6/20 | 1.00 |
| ▸ | P2RX7 | Q99572 | 6/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | IKBKB | O14920 | 1/20 | 0.78 |
| ▸ | CHUK | O15111 | 1/20 | 0.78 |
| ▸ | KDR | P35968 | 1/20 | 0.78 |
| ▸ | FLT3 | P36888 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | MYLK | Q15746 | 1/20 | 0.78 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.78 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.67 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL330629 | 1.00 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL9328867 | 0.90 | TMPRSS4 (0.81) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| Imd-0354 SCHEMBL129165 | 0.88 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812702 | 0.88 | TMPRSS4 (0.94) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| Imd-0354 SCHEMBL29406220 | 0.88 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL4262948 | 0.87 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL330059 | 0.85 | TMPRSS4 (0.90) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL331631 | 0.85 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL29617517 | 0.85 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL11932152 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11246857-B2 | Anti-fungal inhibitors | UNIV JOHNS HOPKINS (US) | 2022-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11246857-B2 | Anti-fungal inhibitors | ERG28, DPM1, HIF1AN | TMPRSS4 1833/4885P2RX1 2594/4885P2RX4 3445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.