Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 12/20 | 1.00 |
| ▸ | P2RX1 | P51575 | 10/20 | 1.00 |
| ▸ | P2RX4 | Q99571 | 6/20 | 1.00 |
| ▸ | P2RX7 | Q99572 | 6/20 | 1.00 |
| ▸ | SLC2A1 | P11166 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | IKBKB | O14920 | 1/20 | 0.78 |
| ▸ | CHUK | O15111 | 1/20 | 0.78 |
| ▸ | KDR | P35968 | 1/20 | 0.78 |
| ▸ | FLT3 | P36888 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | MYLK | Q15746 | 1/20 | 0.78 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.78 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.67 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386800 | 1.00 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL9328867 | 0.90 | TMPRSS4 (0.81) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| Imd-0354 SCHEMBL129165 | 0.88 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL13812702 | 0.88 | TMPRSS4 (0.94) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| Imd-0354 SCHEMBL29406220 | 0.88 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL4262948 | 0.87 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL330059 | 0.85 | TMPRSS4 (0.90) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL29617517 | 0.85 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL331631 | 0.85 | TMPRSS4 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 | |
| SCHEMBL11932152 | 0.84 | P2RX1 (1.00) | TMPRSS4P2RX1P2RX4P2RX7SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200038350-A1 | CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE | DUKE UNIVERSITY | 2020-02-06 | — | — | US | claimed |
| EP-3313388-A1 | CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE | Duke University (US) | 2018-05-02 | — | — | EP | claimed |
| WO-2016210289-A1 | CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE | DUKE UNIVERSITY (US) | 2016-12-29 | — | — | WO | claimed |
| US-20140221411-A1 | 2-HYDROXYARYLAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2014-08-07 | — | — | US | claimed |
| US-20090192122-A2 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-07-30 | — | — | US | claimed |
| US-20080249071-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2008-10-09 | — | — | US | claimed |
| EP-1847263-A2 | Inhibitors against the production and release of inflammatory cytokines | Institute of Medicinal Molecular Design, Inc. (JP) | 2007-10-24 | — | — | EP | claimed |
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2004-12-23 | — | — | US | claimed |
| EP-1352650-A1 | INHIBITORS AGAINST THE PRODUCTION AND RELEASE OF INFLAMMATORY CYTOKINES | Institute of Medicinal Molecular Design, Inc. (JP) | 2003-10-15 | — | — | EP | claimed |
| EP-3653303-B1 | PIPETTE TIP RACK | BIOTIX INC (US) | 2025-02-26 | — | — | EP | disclosed |
| US-12201987-B2 | Pipette tip rack | BIOTIX, INC. (US) | 2025-01-21 | — | — | US | disclosed |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FIRST WAVE BIO, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-11590490-B2 | Pipette tips | BIOTIX, INC. (US) | 2023-02-28 | — | — | US | disclosed |
| US-4115056-A | NATURAL AND SYNTHETIC POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-09-19 | — | — | US | disclosed |
| US-4097229-A | Methods for dyeing or printing using amino-anthraquinone reactive disperse dyes | CIBA-GEIGY AG (CH) | 1978-06-27 | — | — | US | disclosed |
| US-4044029-A | Amino-anthraquinone reactive disperse dyes | CIBA-GEIGY AG (CH) | 1977-08-23 | — | — | US | disclosed |
| US-4022880-A | ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS | LEVER BROTHERS COMPANY (US) | 1977-05-10 | — | — | US | disclosed |
| US-4010252-A | POLYQUATERNARY AMMONIUM COMPOUND, DEODORANTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-03-01 | — | — | US | disclosed |
| US-3983209-A | HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME | ALZA CORPORATION (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192122-A2 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | IL1B, NFKBIA, IL1A | TMPRSS4 1647/4885P2RX1 1538/4885P2RX4 2695/4885 |
| US-20080249071-A1 | INFLAMMATORY CYTOKINE RELEASE INHIBITOR | IL1B, NFKBIA, IL1A | TMPRSS4 1647/4885P2RX1 1538/4885P2RX4 2695/4885 |
| US-20200038350-A1 | CHEMICAL MODULATORS OF SIGNALING PATHWAYS AND THERAPEUTIC USE | SFRP1, FZD7, WNT1 | TMPRSS4 2074/4885P2RX1 3423/4885P2RX4 3784/4885 |
| US-20140221411-A1 | 2-HYDROXYARYLAMIDE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT | TMPRSS2, TMPRSS4, PRSS2 | TMPRSS4 2/4885P2RX1 4273/4885P2RX4 3330/4885 |
| US-20040259877-A1 | Inhibitors against the production and release of inflammatory cytokines | NFKBIA, IL1B, IKBKB | TMPRSS4 3292/4885P2RX1 2316/4885P2RX4 3466/4885 |
| US-11793777-B2 | Methods and compositions for treating conditions associated with an abnormal inflammatory response | FH, CS, ECHS1 | TMPRSS4 2067/4885P2RX1 910/4885P2RX4 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.