Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933590 | 1.00 | VCP (0.44) | VCPHTR1AHTR7HDAC3HDAC1 | |
| SCHEMBL29387407 | 0.93 | HTR1A (0.40) | VCPHTR1AHTR7HDAC3HDAC1 | |
| SCHEMBL16933655 | 0.93 | HTR1A (0.40) | VCPHTR1AHTR7HDAC3HDAC1 | |
| SCHEMBL29387808 | 0.92 | USP2 (0.46) | VCPMEN1KMT2AUSP2CYP3A4 | |
| SCHEMBL16933526 | 0.92 | USP2 (0.46) | VCPMEN1KMT2AUSP2CYP3A4 | |
| SCHEMBL29387387 | 0.91 | VCP (0.45) | VCPHTR1AHTR7HDAC3HDAC1 | |
| SCHEMBL16933449 | 0.91 | VCP (0.45) | VCPHTR1AHTR7HDAC3HDAC1 | |
| SCHEMBL16933422 | 0.88 | MAPK1 (0.43) | HTR1AHTR7MEN1KMT2ALMNA | |
| SCHEMBL29386829 | 0.88 | MAPK1 (0.43) | HTR1AHTR7MEN1KMT2ALMNA | |
| SCHEMBL16933439 | 0.87 | DYRK1A (0.45) | HDAC3HDAC1HDAC2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |