Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933422 | 1.00 | MAPK1 (0.43) | MAPK1HTR1AHTR7HSD17B10USP2 | |
| SCHEMBL29384402 | 0.92 | USP2 (0.49) | MAPK1HSD17B10USP2CYP3A4CYP1A2 | |
| SCHEMBL16933573 | 0.92 | USP2 (0.49) | MAPK1HSD17B10USP2CYP3A4CYP1A2 | |
| SCHEMBL16933590 | 0.88 | VCP (0.44) | MAPK1HTR1AHTR7HSD17B10USP2 | |
| SCHEMBL29387121 | 0.88 | VCP (0.44) | MAPK1HTR1AHTR7HSD17B10USP2 | |
| SCHEMBL29387755 | 0.86 | DHFR (0.40) | MAPK1HSD17B10USP2CYP3A4CYP1A2 | |
| SCHEMBL15579452 | 0.86 | DHFR (0.40) | MAPK1HSD17B10USP2CYP3A4CYP1A2 | |
| SCHEMBL16933655 | 0.86 | HTR1A (0.40) | MAPK1HTR1AHTR7HSD17B10USP2 | |
| SCHEMBL29387407 | 0.86 | HTR1A (0.40) | MAPK1HTR1AHTR7HSD17B10USP2 | |
| SCHEMBL16933676 | 0.85 | USP2 (0.46) | MAPK1HTR1AHSD17B10USP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114533729-A | Glucosylceramide synthase inhibitors | 建新公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-108864076-B | Glucosylceramide synthase inhibitors | 建新公司 | 2022-02-11 | — | — | CN | disclosed |