SCHEMBL29387174

SCHEMBL29387174

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NCC(N)=O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.62
▸ NPY2R P49146 1/20 0.62
▸ NPY4R P50391 1/20 0.62
▸ NPY5R Q15761 1/20 0.62
▸ NTSR1 P30989 11/20 0.60
▸ NTSR2 O95665 9/20 0.60
▸ SORT1 Q99523 7/20 0.58
▸ NMUR2 Q9GZQ4 1/20 0.56
▸ NMUR1 Q9HB89 1/20 0.56
▸ OPRD1 P41143 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612065 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611692 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611524 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611985 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611528 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29612082 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611824 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29612137 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL20707335 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29420258 0.98 NTSR1 (0.60) NPY1RNPY2RNPY4RNPY5RNTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111830154-B Separation method and application of oxytocin and 8 epimers thereof 上海上药第一生化药业有限公司 2022-05-24 — — CN claimed
CN-111912917-B Separation method and application of oxytocin and at least ten impurities 上海上药第一生化药业有限公司 2022-03-15 — — CN claimed
US-20250000947-A1 OXYTOCIN CONJUGATES FOR TREATING NEONATAL DISORDERS ELGAN PHARMA LTD (IL) 2025-01-02 — — US disclosed
CN-119143836-A Polypeptide cyclization method 广州医科大学 2024-12-17 — — CN disclosed
US-20240391950-A1 PEPTIDE CROSSLINKING AGENT AND CROSSLINKED PEPTIDE WHICH IS CROSSLINKED USING SAID CROSSLINKING AGENT KAGOSHIMA UNIVERSITY (JP) 2024-11-28 — — US disclosed
EP-4401793-A1 OXYTOCIN CONJUGATES FOR TREATING NEONATAL DISORDERS Elgan Pharma Ltd. (IL) 2024-07-24 — — EP disclosed
US-20240139278-A1 OXYTOCIN FORMULATION XELLIA PHARMACEUTICALS APS (DK) 2024-05-02 — — US disclosed
EP-4242220-A1 PEPTIDE CROSSLINKING AGENT AND CROSSLINKED PEPTIDE WHICH IS CROSSLINKED USING SAID CROSSLINKING AGENT Kagoshima University (JP) 2023-09-13 — — EP disclosed
US-20230265124-A1 OXYTOCIN ANALOGUES AND METHODS FOR USING THE SAME ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-08-24 — — US disclosed
WO-2023042207-A1 OXYTOCIN CONJUGATES FOR TREATING NEONATAL DISORDERS ELGAN PHARMA LTD (IL) 2023-03-23 — — WO disclosed
US-11414459-B2 Metabolite inspired selective oxytocin receptor agonists Kinoxis Therapeutics Pty Ltd (AU) 2022-08-16 — — US disclosed
CN-111812240-B Separation method and application of oxytocin and three impurities 上海上药第一生化药业有限公司 2022-05-24 — — CN disclosed
CN-111830154-B Separation method and application of oxytocin and 8 epimers thereof 上海上药第一生化药业有限公司 2022-05-24 — — CN disclosed
WO-2022097500-A1 PEPTIDE CROSSLINKING AGENT AND CROSSLINKED PEPTIDE WHICH IS CROSSLINKED USING SAID CROSSLINKING AGENT 国立大学法人 鹿児島大学 2022-05-12 — — WO disclosed
CN-111896642-B Separation method and application of oxytocin and three kinds of deamidation impurities 上海上药第一生化药业有限公司 2022-03-15 — — CN disclosed
CN-111912917-B Separation method and application of oxytocin and at least ten impurities 上海上药第一生化药业有限公司 2022-03-15 — — CN disclosed
WO-2022040110-A2 ALKYLATING AGENT AND COMBINATIONS IN THE TREATMENT OF IMMUNE-RELATED AND LIVER DISEASES, ALZHEIMER'S DISEASES AND FIBROSIS DISEASES LIU SHENG (US) 2022-02-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391950-A1 PEPTIDE CROSSLINKING AGENT AND CROSSLINKED PEPTIDE WHICH IS CROSSLINKED USING SAID CROSSLINKING AGENT PTMA, PTMS, CDC37 NPY1R 564/4885NPY2R 1385/4885NPY4R 1339/4885
US-20240139278-A1 OXYTOCIN FORMULATION OXTR, AVPR2, AVPR1B NPY1R 28/4885NPY2R 26/4885NPY4R 20/4885
US-20230265124-A1 OXYTOCIN ANALOGUES AND METHODS FOR USING THE SAME OXTR, AVPR2, ADM2 NPY1R 38/4885NPY2R 42/4885NPY4R 48/4885
US-11414459-B2 Metabolite inspired selective oxytocin receptor agonists OXTR, AVPR2, AVPR1A NPY1R 14/4885NPY2R 16/4885NPY4R 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback