SCHEMBL20707335

SCHEMBL20707335

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CS)C(=O)NC(CCC(N)=O)C(=O)NC(CC(N)=O)C(=O)NC(CS)C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)NCC(N)=O

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NPY1R P25929 3/20 0.62
▸ NPY2R P49146 1/20 0.62
▸ NPY4R P50391 1/20 0.62
▸ NPY5R Q15761 1/20 0.62
▸ NTSR1 P30989 11/20 0.60
▸ NTSR2 O95665 9/20 0.60
▸ SORT1 Q99523 7/20 0.58
▸ NMUR2 Q9GZQ4 1/20 0.56
▸ NMUR1 Q9HB89 1/20 0.56
▸ OPRD1 P41143 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612065 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611692 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611524 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611985 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29387174 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611528 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29612082 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29611824 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29612137 1.00 NPY1R (0.62) NPY1RNPY2RNPY4RNPY5RNTSR1
SCHEMBL29420258 0.98 NTSR1 (0.60) NPY1RNPY2RNPY4RNPY5RNTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10806770-B2 Powder formulation MONASH UNIVERSITY (AU) 2020-10-20 — — US disclosed
EP-3438121-B1 LIQUID PHASE SYNTHESIS METHOD FOR OXYTOCIN USING POLYPEPTIDES LANZHOU KAIBO PHARMACEUTICAL CO LTD (CN) 2020-09-30 — — EP disclosed
US-20190125824-A1 POWDER FORMULATION MONASH UNIVERSITY (AU) 2019-05-02 — — US disclosed
EP-3438121-A1 LIQUID PHASE SYNTHESIS METHOD FOR OXYTOCIN USING POLYPEPTIDES Lanzhou Kaibo Pharmaceutical Co., Ltd. (CN) 2019-02-06 — — EP disclosed
CN-107106641-A Powder formulation 葛兰素史密斯克莱知识产权发展有限公司 2017-08-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10806770-B2 Powder formulation OXTR, CRH, CRHBP NPY1R 156/4885NPY2R 61/4885NPY4R 163/4885
US-20190125824-A1 POWDER FORMULATION OXTR, CRH, CRHBP NPY1R 149/4885NPY2R 60/4885NPY4R 152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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